Pharmacogenetics of tuberculosis treatment toxicity and effectiveness in a large Brazilian cohort

Genetic polymorphisms have been associated with risk of antituberculosis treatment toxicity. We characterized associations with adverse events and treatment failure/recurrence among adults treated for tuberculosis in Brazil. Participants were followed in Regional Prospective Observational Research i...

Full description

Saved in:

Bibliographic Details
Published in:	Pharmacogenetics and genomics Vol. 35; no. 2; p. 55
Main Authors:	Amorim, Gustavo, Jaworski, James, Yang, Jing, Cordeiro-Santos, Marcelo, Kritski, Afrânio L, Figueiredo, Marina C, Turner, Megan, Andrade, Bruno B, Velez Edwards, Digna R, Santos, Adalberto R, Rolla, Valeria C, Sterling, Timothy R, Haas, David W
Format:	Journal Article
Language:	English
Published:	United States 01.02.2025
Subjects:	Adult Antitubercular Agents - adverse effects Antitubercular Agents - therapeutic use Arylamine N-Acetyltransferase - genetics Brazil Cohort Studies Female Glutathione Transferase - genetics Humans Liver-Specific Organic Anion Transporter 1 Male Middle Aged Pharmacogenetics Polymorphism, Single Nucleotide Pregnane X Receptor Prospective Studies Treatment Outcome Tuberculosis - drug therapy Tuberculosis - genetics Tuberculosis, Pulmonary - drug therapy Tuberculosis, Pulmonary - genetics Brazil
ISSN:	1744-6880, 1744-6880
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!