Enoxaparin improves COVID-19 by reducing Neutrophils Extracellular Traps (NETs) production

COVID-19 causes consequences such as imbalance of the immune system and thrombotic events. During the infection process, NETs in excess induce a pro-inflammatory response and disseminated intravascular coagulation. We evaluated the role of enoxaparin as a potential inhibitor of NETs. K18-hACE2 anima...

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Vydáno v:	Clinical immunology (Orlando, Fla.) Ročník 257; s. 109836
Hlavní autoři:	Córneo, Emily S., Veras, Flavio Protasio, Gomes, Giovanni F., Schneider, Ayda H., Manuella, Bruna, Almeida, Cicero J.L.R., Silva, Camila M., Martins, Ronaldo B., Batah, Sabrina S., Simon, Carla S., Prestes, Gabriele da S., Alves-Filho, José Carlos, Arruda, Eurico, Louzada-Junior, Paulo, de Oliveira, Renê D.R., Fabro, Alexandre T., Cunha, Thiago M., Cunha, Fernando Queiroz, Dal-Pizzol, Felipe
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Elsevier Inc 01.12.2023
Témata:	Animals COVID-19 Enoxaparin Enoxaparin - pharmacology Extracellular Traps Humans Inflammatory markers Lung injury NETs Neutrophils SARS-CoV-2 PBS Enoxaparin Inflammatory markers PFA MPO H3Cit COVID-19 SOFA SARS-CoV-2 NETs Enox NE Lung injury PAD-4
ISSN:	1521-6616, 1521-7035, 1521-7035
On-line přístup:	Získat plný text
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