Targeting a Novel ER/HOXB7 Signaling Loop in Tamoxifen-Resistant Breast Cancer

The majority of patients with breast cancer present with an estrogen receptor-positive (ER(+)) tumor, and the endocrine agent tamoxifen is a mainstay for their treatment. Unfortunately, however, resistance remains a major problem because most patients who respond eventually have a recurrence. Thus,...

Celý popis

Podrobná bibliografia

Vydané v:	Cancer discovery Ročník 5; číslo 9; s. 909
Hlavní autori:	Heideman, Marinus R, Frei, Anna, Hynes, Nancy E
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.09.2015
Predmet:	Animals Antineoplastic Agents, Hormonal - pharmacology Drug Resistance, Neoplasm - genetics Estrogen Receptor alpha - metabolism Female Gene Expression Regulation, Neoplastic Homeodomain Proteins - metabolism Humans Receptor, ErbB-2 - metabolism
ISSN:	2159-8290, 2159-8290
On-line prístup:	Zistit podrobnosti o prístupe
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!