Development and validation of simple spectrophotometric and chemometric methods for simultaneous determination of empagliflozin and metformin: Applied to recently approved pharmaceutical formulation

New univariate spectrophotometric method and multivariate chemometric approach were developed and compared for simultaneous determination of empagliflozin and metformin manipulating their zero order absorption spectra with application on their pharmaceutical preparation. Sample enrichment technique...

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Bibliographic Details
Published in:	Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy Vol. 168; pp. 118 - 122
Main Author:	Ayoub, Bassam M.
Format:	Journal Article
Language:	English
Published:	England Elsevier B.V 05.11.2016
Subjects:	Benzhydryl Compounds - analysis Chemometry Empagliflozin Glucosides - analysis Hypoglycemic Agents - analysis Least-Squares Analysis Limit of Detection Metformin Metformin - analysis Partial least squares Pharmaceutical preparation Simultaneous equation Spectrophotometry - methods Tablets Pharmaceutical preparation Empagliflozin Metformin Chemometry Partial least squares Simultaneous equation
ISSN:	1386-1425, 1873-3557, 1873-3557
Online Access:	Get full text
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