The Genetics of Chronic Itch: Gene Expression in the Skin of Patients with Atopic Dermatitis and Psoriasis with Severe Itch

To identify itch-related mediators and receptors that are differentially expressed in pruritic skin, we used RNA sequencing to analyze the complete transcriptome in skin from paired itchy, lesional and nonitchy, nonlesional skin biopsies from 25 patients with atopic dermatitis and 25 patients with p...

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Vydané v:	Journal of investigative dermatology Ročník 138; číslo 6; s. 1311
Hlavní autori:	Nattkemper, Leigh A, Tey, Hong Liang, Valdes-Rodriguez, Rodrigo, Lee, Helen, Mollanazar, Nicholas K, Albornoz, Christian, Sanders, Kristen M, Yosipovitch, Gil
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.06.2018
Predmet:	Adult Biopsy Chronic Disease Dermatitis, Atopic - complications Dermatitis, Atopic - genetics Dermatitis, Atopic - immunology Dermatitis, Atopic - pathology Female Gene Expression Profiling Healthy Volunteers Humans Male Middle Aged Pruritus - genetics Pruritus - immunology Pruritus - pathology Psoriasis - complications Psoriasis - genetics Psoriasis - immunology Psoriasis - pathology Sequence Analysis, RNA Skin - pathology Transcriptome - immunology
ISSN:	1523-1747, 1523-1747
On-line prístup:	Zistit podrobnosti o prístupe
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