The Genetics of Chronic Itch: Gene Expression in the Skin of Patients with Atopic Dermatitis and Psoriasis with Severe Itch

To identify itch-related mediators and receptors that are differentially expressed in pruritic skin, we used RNA sequencing to analyze the complete transcriptome in skin from paired itchy, lesional and nonitchy, nonlesional skin biopsies from 25 patients with atopic dermatitis and 25 patients with p...

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Bibliographic Details
Published in:	Journal of investigative dermatology Vol. 138; no. 6; p. 1311
Main Authors:	Nattkemper, Leigh A, Tey, Hong Liang, Valdes-Rodriguez, Rodrigo, Lee, Helen, Mollanazar, Nicholas K, Albornoz, Christian, Sanders, Kristen M, Yosipovitch, Gil
Format:	Journal Article
Language:	English
Published:	United States 01.06.2018
Subjects:	Adult Biopsy Chronic Disease Dermatitis, Atopic - complications Dermatitis, Atopic - genetics Dermatitis, Atopic - immunology Dermatitis, Atopic - pathology Female Gene Expression Profiling Healthy Volunteers Humans Male Middle Aged Pruritus - genetics Pruritus - immunology Pruritus - pathology Psoriasis - complications Psoriasis - genetics Psoriasis - immunology Psoriasis - pathology Sequence Analysis, RNA Skin - pathology Transcriptome - immunology
ISSN:	1523-1747, 1523-1747
Online Access:	Get more information
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