Effectiveness of cognitive behavioral therapy for perinatal maternal depression, anxiety and stress: A systematic review and meta-analysis of randomized controlled trials

Cognitive behavioral therapy (CBT) has been widely studied in prenatal or postnatal depression, with much less research on anxiety and stress. This meta-analysis aims to comprehensively evaluate CBT efficacy for perinatal depression, anxiety and stress in the short term (from baseline to immediately...

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Bibliographic Details
Published in:Clinical psychology review Vol. 92; p. 102129
Main Authors: Li, Xinyuan, Laplante, David P., Paquin, Vincent, Lafortune, Sandra, Elgbeili, Guillaume, King, Suzanne
Format: Journal Article
Language:English
Published: United States Elsevier Ltd 01.03.2022
Subjects:
Anxiety
Anxiety - therapy
Anxiety Disorders - therapy
Cognitive Behavioral Therapy
Depression
Depression - therapy
Female
Humans
Meta-analysis
Perinatal
Randomized Controlled Trials as Topic
Stress
Perinatal
Depression
Anxiety
Stress
Cognitive behavioral therapy
Meta-analysis
ISSN:0272-7358, 1873-7811, 1873-7811
Online Access:Get full text
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Summary:Cognitive behavioral therapy (CBT) has been widely studied in prenatal or postnatal depression, with much less research on anxiety and stress. This meta-analysis aims to comprehensively evaluate CBT efficacy for perinatal depression, anxiety and stress in the short term (from baseline to immediately post-intervention) and in the long term (from baseline to the end of follow-up). Five databases were searched. We included 79 randomized controlled trials (RCTs) and quasi-RCTs assessing the efficacy of CBT during pregnancy and the first year postpartum. Primary outcome was the mean score change in depression, anxiety and stress. CBT-only and CBT plus other interventions were effective for perinatal maternal depression in the short term (SMD −0.69, 95% CI: −0.83, −0.55) and long term (SMD −0.59, 95% CI −0.75, −0.42). CBT-only had both short- and long-term efficacy for perinatal anxiety (short term: SMD −0.63, 95% CI −0.85, −0.42; long term: SMD −0.71, 95% CI −1.02, −0.39) and short-term efficacy for perinatal stress (SMD −0.96, 95% CI −1.40, −0.52). Overall, CBT was effective for perinatal maternal depression, anxiety and stress. CBT-only exhibited short-term efficacy for perinatal depression, anxiety and stress, and long-term efficacy for perinatal depression and anxiety. Subgroup analyses suggested that CBT-only was effective across a wide variety of modalities. •Overall, CBT is effective for perinatal maternal depression, anxiety and stress.•CBT-only is effective for perinatal depression in low-income women.•Partner-inclusive CBT-only is effective for depression, anxiety and stress.•CBT-only is effective in treating and preventing depression, anxiety and stress.•CBT plus other interventions showed short- and long-term efficacy for depression.
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ISSN:0272-7358
1873-7811
1873-7811
DOI:10.1016/j.cpr.2022.102129