Effects of symptom clusters and depression on the quality of life in patients with advanced lung cancer

People with advanced lung cancer experience later symptoms after treatment that is related to poorer psychosocial and quality of life (QOL) outcomes. The purpose of this study was to identify the effect of symptom clusters and depression on the QOL of patients with advanced lung cancer. A sample of...

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Bibliographic Details
Published in:European journal of cancer care Vol. 27; no. 1; pp. e12508 - n/a
Main Authors: Choi, S., Ryu, E.
Format: Journal Article
Language:English
Published: England John Wiley & Sons, Inc 01.01.2018
Subjects:
Adenocarcinoma - economics
Adenocarcinoma - psychology
Adult
Aged
Antidepressive Agents - therapeutic use
Cancer
Carcinoma, Non-Small-Cell Lung - economics
Carcinoma, Non-Small-Cell Lung - psychology
Cluster analysis
Cost of Illness
Demographics
Depressive Disorder - drug therapy
Depressive Disorder - economics
Depressive Disorder - etiology
Educational Status
Epidemiology
Factor analysis
Fatigue
Female
Health Status
Humans
Lung cancer
Lung Neoplasms - economics
Lung Neoplasms - psychology
Male
Marital Status
Mental depression
Middle Aged
Palliative care
Patients
Pharmacology
Quality of life
Quality of Life - psychology
Regression analysis
Regression models
Small Cell Lung Carcinoma - economics
Small Cell Lung Carcinoma - psychology
symptoms
South Korea
lung cancer
symptoms
quality of life
ISSN:0961-5423, 1365-2354, 1365-2354
Online Access:Get full text
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Summary:People with advanced lung cancer experience later symptoms after treatment that is related to poorer psychosocial and quality of life (QOL) outcomes. The purpose of this study was to identify the effect of symptom clusters and depression on the QOL of patients with advanced lung cancer. A sample of 178 patients with advanced lung cancer at the National Cancer Center in Korea completed a demographic questionnaire, the M.D. Anderson Symptom Inventory–Lung Cancer, the Center for Epidemiological Studies Depression Scale, and the Functional Assessment of Cancer Therapy–General scale. The most frequently experienced symptom was fatigue, anguish was the most severe symptom‐associated distress, and 28.9% of participants were clinically depressed. Factor analysis was used to identify symptom clusters based on the severity of patients' symptom experiences. Three symptom clusters were identified: treatment‐associated, lung cancer and psychological symptom clusters. The regression model found a significant negative impact on QOL for depression and lung cancer symptom cluster. Age as the control variable was found to be significant impact on QOL. Therefore, psychological screening and appropriate intervention is an essential part of advanced cancer care. Both pharmacological and non‐pharmacological approaches for alleviating depression may help to improve the QOL of lung cancer patients.
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ISSN:0961-5423
1365-2354
1365-2354
DOI:10.1111/ecc.12508