Hypoxia caused by unilateral nasal obstruction decreases mandibular density in rats through inhibition of Cyp1a1 expression

Background Oral breathing has an important impact on morphology and bone mineral density (BMD) in a mandible. This study aimed to investigate the hub genes and mechanism regulating the mandibular BMD decrease induced by nasal obstruction. Methods A unilateral nasal obstruction model was established...

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Veröffentlicht in:	Journal of oral pathology & medicine Jg. 52; H. 8; S. 786 - 794
Hauptverfasser:	Xu, Yixin, Wang, Yixin, Xiao, Hui, Li, Yongming
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Denmark Wiley Subscription Services, Inc 01.09.2023
Schlagworte:	Animal models Bone mineral density Bone turnover Computed tomography Cytochrome P450 Homeostasis Hypoxia Mandible Mesenchymal stem cells nasal respiratory obstruction Osteoprotegerin respiratory changes TRANCE protein transcriptome sequencing Transcriptomes mandible bone mineral density nasal respiratory obstruction transcriptome sequencing respiratory changes
ISSN:	0904-2512, 1600-0714, 1600-0714
Online-Zugang:	Volltext
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