Proposal for an optimised definition of adverse pathology (unfavourable histology) that predicts metastatic risk in prostatic adenocarcinoma independent of grade group and pathological stage

Aims Histological grading of prostate cancer is a powerful prognostic tool, but current criteria for grade assignment are not fully optimised. Our goal was to develop and test a simplified histological grading model, based heavily on large cribriform/intraductal carcinoma, with optimised sensitivity...

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Bibliographic Details
Published in:	Histopathology Vol. 85; no. 4; pp. 598 - 613
Main Authors:	Nguyen, Jane K, Harik, Lara R, Klein, Eric A, Li, Jianbo, Corrigan, Dillon, Liu, Shiguang, Chan, Emily, Hawley, Sarah, Auman, Heidi, Newcomb, Lisa F, Carroll, Peter R, Cooperberg, Matthew R, Filson, Christopher P, Simko, Jeff P, Nelson, Peter S, Tretiakova, Maria S, Troyer, Dean, True, Lawrence D, Vakar‐Lopez, Funda, Weight, Christopher J, Lin, Daniel W, Brooks, James D, McKenney, Jesse K
Format:	Journal Article
Language:	English
Published:	England Wiley Subscription Services, Inc 01.10.2024
Subjects:	Adenocarcinoma Adenocarcinoma - pathology Aged Cancer Cohort Studies cribriform Gleason grade Histology Humans Kaplan-Meier Estimate Male Metastases Metastasis Middle Aged Neoplasm Grading Neoplasm Metastasis - pathology Neoplasm Staging Nomograms Prognosis Proportional Hazards Models Prostate Prostate cancer Prostate carcinoma Prostatectomy Prostatic Neoplasms - pathology Prostatic Neoplasms - surgery Sensitivity analysis adenocarcinoma prostate Gleason cribriform grade
ISSN:	0309-0167, 1365-2559, 1365-2559
Online Access:	Get full text
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