Animal models of human anthrax: The Quest for the Holy Grail

Anthrax is rare among humans, few data can be collected from infected individuals and they provide a fragmentary view of the dynamics of infection and human host–pathogen interactions. Therefore, the development of animal models is necessary. Anthrax has the particularity of being a toxi-infection,...

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Vydané v:	Molecular aspects of medicine Ročník 30; číslo 6; s. 467 - 480
Hlavný autor:	Goossens, Pierre L.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England Elsevier Ltd 01.12.2009
Predmet:	Animal model Animals Anthrax Anthrax - classification Anthrax - microbiology Anthrax - physiopathology Anthrax - transmission Bacillus anthracis Bacillus anthracis - pathogenicity Bacterial infection Disease Models, Animal Guinea pig Host-Pathogen Interactions Humans Inhalation Exposure Lung Mediastinal lymph node Mouse Non-human primate Pleura Rabbit Rat Spores, Bacterial - metabolism Toxin Bacillus anthracis Animal model Rat Lung Rabbit Bacterial infection Toxin Guinea pig Mouse Anthrax Non-human primate Mediastinal lymph node Pleura
ISSN:	0098-2997, 1872-9452, 1872-9452
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