BK virus large T antigen: interactions with the retinoblastoma family of tumor suppressor proteins and effects on cellular growth control

BK virus (BKV) is a polyomavirus which infects a large percentage of the human population. It is a potent transforming agent and is tumorigenic in rodents. BKV DNA has also been found in human brain, pancreatic islet, and urinary tract tumors, implicating this virus in neoplastic processes. BKV T an...

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Bibliographic Details
Published in:	Journal of virology Vol. 70; no. 4; p. 2378
Main Authors:	Harris, K F, Christensen, J B, Imperiale, M J
Format:	Journal Article
Language:	English
Published:	United States 01.04.1996
Subjects:	Animals Antigens, Polyomavirus Transforming - metabolism Antigens, Polyomavirus Transforming - physiology BK Virus - immunology BK Virus - physiology Cell Division Cell Line Cell Transformation, Viral - physiology Cercopithecus aethiops Humans Nuclear Proteins - metabolism Phosphoproteins - metabolism Protein Binding Proteins Retinoblastoma Protein - metabolism Retinoblastoma-Like Protein p107 Retinoblastoma-Like Protein p130 Tumor Suppressor Protein p53 - metabolism
ISSN:	0022-538X
Online Access:	Get more information
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