Ferric Carboxymaltose in Heart Failure with Iron Deficiency

In patients with heart failure with reduced ejection fraction and iron deficiency, ferric carboxymaltose therapy did not appear to differ from placebo in the composite of death, heart-failure hospitalizations, or walk distance.

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Bibliographic Details
Published in:The New England journal of medicine Vol. 389; no. 11; pp. 975 - 986
Main Authors: Mentz, Robert J., Garg, Jyotsna, Rockhold, Frank W., Butler, Javed, De Pasquale, Carmine G., Ezekowitz, Justin A., Lewis, Gregory D., O’Meara, Eileen, Ponikowski, Piotr, Troughton, Richard W., Wong, Yee Weng, She, Lilin, Harrington, Josephine, Adamczyk, Robert, Blackman, Nicole, Hernandez, Adrian F.
Format: Journal Article
Language:English
Published: United States Massachusetts Medical Society 14.09.2023
Subjects:
Administration, Intravenous
Ambulatory Care
Anemia
Cardiology
Cardiology General
Clinical trials
Confidence intervals
Congestive heart failure
Coronaviruses
COVID-19
Datasets
Death
Double-Blind Method
Ejection fraction
Ferric Compounds - administration & dosage
Ferric Compounds - adverse effects
Ferric Compounds - therapeutic use
Heart Failure
Heart Failure - complications
Heart Failure - drug therapy
Heart Failure - physiopathology
Hematology
Hemoglobin
Hospitalization
Humans
Iron
Iron Deficiencies - complications
Iron Deficiencies - drug therapy
Iron deficiency
Nutrient deficiency
Oncology
Patients
Placebos
Quality of Life
Statistical analysis
Stroke Volume
Ventricle
Ventricular Function, Left
ISSN:0028-4793, 1533-4406, 1533-4406
Online Access:Get full text
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Description
Summary:In patients with heart failure with reduced ejection fraction and iron deficiency, ferric carboxymaltose therapy did not appear to differ from placebo in the composite of death, heart-failure hospitalizations, or walk distance.
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ISSN:0028-4793
1533-4406
1533-4406
DOI:10.1056/NEJMoa2304968