Effects of Polyhalogenated Aromatic Compounds on Porphyrin Metabolism

Heme production is a vital metabolic process that occurs in the bone marrow and liver. Porphyrins are unused by-products of this biosynthetic process and normally occur in urine and other body fluids in low concentrations. Various disorders can disrupt the heme biosynthetic process, causing greater...

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Bibliographic Details
Published in:	Environmental health perspectives Vol. 60; pp. 139 - 143
Main Author:	Hill, Robert H.
Format:	Journal Article
Language:	English
Published:	United States National Institute of Environmental Health Sciences. National Institutes of Health. Department of Health, Education and Welfare 01.05.1985
Subjects:	Animals Biologic Indicators of Human Toxicity Biosynthesis Chemical and Drug Induced Liver Injury Chemical hazards Chromatography, High Pressure Liquid Cogeneration Heme - biosynthesis Hepatic porphyria Humans Hydrocarbons, Halogenated - adverse effects Hydrocarbons, Halogenated - toxicity Liver Porphyria cutanea tarda Porphyrias Porphyrias - chemically induced Porphyrins Porphyrins - metabolism Porphyrins - urine Urine Uroporphyrinogen Decarboxylase - antagonists & inhibitors Uroporphyrins
ISSN:	0091-6765, 1552-9924
Online Access:	Get full text
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