Adaptive kernelized evidential clustering for automatic 3D tumor segmentation in FDG–PET images

Automatically and reliably delineating tumor contours in noisy and blurring PET images is a challenging work in clinical oncology. In this paper, we introduce a specific unsupervised learning method to this end. More specifically, a robust clustering algorithm with spatial knowledge enhancement is d...

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Bibliographic Details
Published in:Multimedia systems Vol. 25; no. 2; pp. 127 - 133
Main Authors: Wang, Fan, Lian, Chunfeng, Vera, Pierre, Ruan, Su
Format: Journal Article
Language:English
Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.04.2019
Springer Nature B.V
Springer Verlag
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ISSN:0942-4962, 1432-1882
Online Access:Get full text
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Summary:Automatically and reliably delineating tumor contours in noisy and blurring PET images is a challenging work in clinical oncology. In this paper, we introduce a specific unsupervised learning method to this end. More specifically, a robust clustering algorithm with spatial knowledge enhancement is developed in the framework of belief functions, a formal and powerful tool for modeling and reasoning with uncertain and/or imprecise information. Diverse patch-based image features are extracted to comprehensively describe PET image voxels. Then, informative input features are iteratively selected to learn an adaptive kernel-induced metric in an unsupervised way, so as to precisely grouping voxels into different clusters. The effectiveness of the proposed method has been evaluated on FDG–PET images for lung tumor patients.
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ISSN:0942-4962
1432-1882
DOI:10.1007/s00530-017-0579-0