Black-blood diffusion-weighted EPI acquisition of the liver with parallel imaging: comparison with a standard T2-weighted sequence for detection of focal liver lesions

To evaluate the performance of black-blood diffusion-weighted (DW)-EPI sequences with parallel imaging for the detection of focal liver lesions in comparison with a standard T2-weighted (T2-w) sequence. Twenty patients with known or suspected focal liver lesions underwent liver MRI using a DW-EPI se...

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Vydané v:Investigative radiology Ročník 43; číslo 4; s. 261
Hlavní autori: Zech, Christoph J, Herrmann, Karin A, Dietrich, Olaf, Horger, Wilhelm, Reiser, Maximilian F, Schoenberg, Stefan O
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: United States 01.04.2008
Predmet:
Adult
Aged
Aged, 80 and over
Contrast Media
Dextrans
Echo-Planar Imaging - methods
Female
Ferrosoferric Oxide
Gadolinium DTPA
Humans
Iron
Liver Diseases - diagnosis
Magnetic Resonance Imaging
Magnetite Nanoparticles
Male
Middle Aged
Oxides
Predictive Value of Tests
Retrospective Studies
Sensitivity and Specificity
Statistics, Nonparametric
ISSN:0020-9996
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Shrnutí:To evaluate the performance of black-blood diffusion-weighted (DW)-EPI sequences with parallel imaging for the detection of focal liver lesions in comparison with a standard T2-weighted (T2-w) sequence. Twenty patients with known or suspected focal liver lesions underwent liver MRI using a DW-EPI sequence with a b-value of 50 S/mm2 (TR/TE 2200/50 ms) and a standard fat-saturated T2-w sequence (TR/TE 2800/107 ms) with 6-mm slice thickness on a 1.5-T MRI system. Both sequences used parallel imaging with an acceleration factor of 2. Overall image quality and degree of artifacts were compared on a 5-point scale with 5 being the most desirable score. The detection rate and the level of confidence with regard to lesion detection were evaluated for both sequences in comparison to a contrast-enhanced (Gadolinium and SPIO) MR examination, which was used as the standard of reference. The DW-EPI sequence showed significantly (P < 0.05) improved overall image quality (average score 4.15 vs. 3.63) and fewer artifacts (average score 4.2 vs. 3.5) in comparison with the T2-w sequence. The sensitivity for lesion detection was superior in the DW-EPI sequence (83% vs. 61%). The level of confidence in the detection of focal liver lesions was also superior for the DW-EPI sequence in comparison with the T2-w sequence (average score 3.9 vs. 3.2). DW-EPI sequences for liver-imaging are feasible with parallel imaging and show excellent image quality. They may contribute to more easy and confident lesion detection in comparison with T2-w sequences.
Bibliografia:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0020-9996
DOI:10.1097/RLI.0b013e31816200b5