Network Classification Based on Reducibility With Respect to the Stability of Canalizing Power of Genes in a Gene Regulatory Network - A Boolean Network Modeling Perspective

A key objective of studying biological systems is to design therapeutic intervention strategies for beneficially altering cell dynamics. Derivation of control policies is hindered by the high-dimensional state spaces associated with gene regulatory networks. Hence, it is critical to reduce the netwo...

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Veröffentlicht in:IEEE/ACM transactions on computational biology and bioinformatics Jg. 19; H. 1; S. 558 - 568
Hauptverfasser: Kim, Eunji, Ivanov, Ivan, Dougherty, Edward R.
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States IEEE 01.01.2022
The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
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ISSN:1545-5963, 1557-9964, 1557-9964
Online-Zugang:Volltext
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