Controlled disassembly of peptide amphiphile fibres
In this paper, the introduction of both a methionine residue and a nitrobenzyl derivative as a labile linker between the peptide part and the hydrophobic alkyl chain of a peptide amphiphile are presented. These modifications are shown not to inhibit the formation of structured assemblies that analog...
Uložené v:
| Vydané v: | Journal of peptide science Ročník 14; číslo 2; s. 127 - 133 |
|---|---|
| Hlavní autori: | , , , , , , , , |
| Médium: | Journal Article |
| Jazyk: | English |
| Vydavateľské údaje: |
Chichester, UK
John Wiley & Sons, Ltd
01.02.2008
|
| Predmet: | |
| ISSN: | 1075-2617, 1099-1387 |
| On-line prístup: | Získať plný text |
| Tagy: |
Pridať tag
Žiadne tagy, Buďte prvý, kto otaguje tento záznam!
|
| Abstract | In this paper, the introduction of both a methionine residue and a nitrobenzyl derivative as a labile linker between the peptide part and the hydrophobic alkyl chain of a peptide amphiphile are presented. These modifications are shown not to inhibit the formation of structured assemblies that analogous peptide amphiphiles lacking the linkers are able to form. Moreover, the introduction of either labile linker allows removal of the peptide amphiphile's stabilizing hydrophobic moieties to initiate a controlled disassembly of fibre aggregates. This is achieved by either treatment with CNBr or UV irradiation, respectively. These disassembly mechanisms could be the starting point for methodology that allows further manipulation of self‐assembled peptide amphiphile architectures. Copyright © 2007 European Peptide Society and John Wiley & Sons, Ltd. |
|---|---|
| AbstractList | In this paper, the introduction of both a methionine residue and a nitrobenzyl derivative as a labile linker between the peptide part and the hydrophobic alkyl chain of a peptide amphiphile are presented. These modifications are shown not to inhibit the formation of structured assemblies that analogous peptide amphiphiles lacking the linkers are able to form. Moreover, the introduction of either labile linker allows removal of the peptide amphiphile's stabilizing hydrophobic moieties to initiate a controlled disassembly of fibre aggregates. This is achieved by either treatment with CNBr or UV irradiation, respectively. These disassembly mechanisms could be the starting point for methodology that allows further manipulation of self-assembled peptide amphiphile architectures. In this paper, the introduction of both a methionine residue and a nitrobenzyl derivative as a labile linker between the peptide part and the hydrophobic alkyl chain of a peptide amphiphile are presented. These modifications are shown not to inhibit the formation of structured assemblies that analogous peptide amphiphiles lacking the linkers are able to form. Moreover, the introduction of either labile linker allows removal of the peptide amphiphile's stabilizing hydrophobic moieties to initiate a controlled disassembly of fibre aggregates. This is achieved by either treatment with CNBr or UV irradiation, respectively. These disassembly mechanisms could be the starting point for methodology that allows further manipulation of self-assembled peptide amphiphile architectures.In this paper, the introduction of both a methionine residue and a nitrobenzyl derivative as a labile linker between the peptide part and the hydrophobic alkyl chain of a peptide amphiphile are presented. These modifications are shown not to inhibit the formation of structured assemblies that analogous peptide amphiphiles lacking the linkers are able to form. Moreover, the introduction of either labile linker allows removal of the peptide amphiphile's stabilizing hydrophobic moieties to initiate a controlled disassembly of fibre aggregates. This is achieved by either treatment with CNBr or UV irradiation, respectively. These disassembly mechanisms could be the starting point for methodology that allows further manipulation of self-assembled peptide amphiphile architectures. In this paper, the introduction of both a methionine residue and a nitrobenzyl derivative as a labile linker between the peptide part and the hydrophobic alkyl chain of a peptide amphiphile are presented. These modifications are shown not to inhibit the formation of structured assemblies that analogous peptide amphiphiles lacking the linkers are able to form. Moreover, the introduction of either labile linker allows removal of the peptide amphiphile's stabilizing hydrophobic moieties to initiate a controlled disassembly of fibre aggregates. This is achieved by either treatment with CNBr or UV irradiation, respectively. These disassembly mechanisms could be the starting point for methodology that allows further manipulation of self‐assembled peptide amphiphile architectures. Copyright © 2007 European Peptide Society and John Wiley & Sons, Ltd. |
| Author | van Hest, Jan C. M. Schulten, Ines Heckenmüller, Lisa Minten, Inge J. van Kalkeren, Henri Sliepen, Kwinten Smittenaar, Peter Meijer, Joris T. Löwik, Dennis W. P. M. |
| Author_xml | – sequence: 1 givenname: Dennis W. P. M. surname: Löwik fullname: Löwik, Dennis W. P. M. email: D.Lowik@science.ru.nl – sequence: 2 givenname: Joris T. surname: Meijer fullname: Meijer, Joris T. – sequence: 3 givenname: Inge J. surname: Minten fullname: Minten, Inge J. – sequence: 4 givenname: Henri surname: van Kalkeren fullname: van Kalkeren, Henri – sequence: 5 givenname: Lisa surname: Heckenmüller fullname: Heckenmüller, Lisa – sequence: 6 givenname: Ines surname: Schulten fullname: Schulten, Ines – sequence: 7 givenname: Kwinten surname: Sliepen fullname: Sliepen, Kwinten – sequence: 8 givenname: Peter surname: Smittenaar fullname: Smittenaar, Peter – sequence: 9 givenname: Jan C. M. surname: van Hest fullname: van Hest, Jan C. M. |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/18044820$$D View this record in MEDLINE/PubMed |
| BookMark | eNqF0MtKxDAUgOEginNRfAPpShfSMbdespTiDQYUnH1ImhOMpNPadJB5e1NmdKGIcCAH8nEW_wwdrts1IHRG8IJgTK-7UC9ELg7QlGAhUsLK4nDciyylOSkmaBbCG8bxL8uP0YSUmPOS4iliVbse-tZ7MIlxQYUAjfbbpLVJB93gDCSq6V5dHA-JdbqHcIKOrPIBTvfvHK3ublfVQ7p8un-sbpZpzXguUqtVngO1mmGKGbPAjRGGkqJUGbDMaCUMzjnYUnEMVuOM8JwzClobjks2Rxe7s13fvm8gDLJxoQbv1RraTZAFpgVnRfYvpIRkTFAS4fkebnQDRna9a1S_lV85Ikh3oO7bEHqwsnaDGtzYSDkvCZZjbhlzy5g7-ssf_vvkL3m1kx-x4_YvJp9fqlF_AnZijNU |
| CitedBy_id | crossref_primary_10_1039_B814549K crossref_primary_10_1007_s11426_014_5225_5 crossref_primary_10_1088_0957_4484_27_40_402002 crossref_primary_10_1039_b914342b crossref_primary_10_1007_s11030_013_9481_7 crossref_primary_10_3892_etm_2019_8368 crossref_primary_10_1016_j_bpj_2013_05_047 crossref_primary_10_1039_c3fd00055a |
| Cites_doi | 10.1002/macp.200600559 10.1039/b607706d 10.1016/0003-2697(70)90146-6 10.1002/adma.200602295 10.1021/ja060759w 10.1016/S0040-4020(97)00029-X 10.1002/bip.20663 10.1039/b303749e 10.1016/j.cbpa.2006.09.019 10.1021/la047578x 10.1002/mabi.200600226 10.1021/ja054719o 10.1111/j.1399-3011.1990.tb00939.x 10.1016/S1367-5931(02)00391-5 10.1021/jo034167x 10.1126/science.1093783 10.1039/b516805h 10.1021/ja035360b 10.1039/b212638a 10.1002/anie.200603681 10.1039/b608929a 10.1007/12_081 10.1021/ja057100v |
| ContentType | Journal Article |
| Copyright | Copyright © 2007 European Peptide Society and John Wiley & Sons, Ltd. |
| Copyright_xml | – notice: Copyright © 2007 European Peptide Society and John Wiley & Sons, Ltd. |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 7QO 8FD FR3 P64 7X8 |
| DOI | 10.1002/psc.969 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed Biotechnology Research Abstracts Technology Research Database Engineering Research Database Biotechnology and BioEngineering Abstracts MEDLINE - Academic |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Engineering Research Database Biotechnology Research Abstracts Technology Research Database Biotechnology and BioEngineering Abstracts MEDLINE - Academic |
| DatabaseTitleList | MEDLINE MEDLINE - Academic CrossRef Engineering Research Database |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Chemistry |
| EISSN | 1099-1387 |
| EndPage | 133 |
| ExternalDocumentID | 18044820 10_1002_psc_969 PSC969 |
| Genre | article Journal Article |
| GroupedDBID | --- .3N .GA .Y3 05W 0R~ 10A 1L6 1OB 1OC 1ZS 31~ 33P 3SF 3WU 4.4 50Y 50Z 51W 51X 52M 52N 52O 52P 52S 52T 52U 52W 52X 53G 5GY 5VS 66C 702 7PT 8-0 8-1 8-3 8-4 8-5 8UM 930 A03 AAESR AAEVG AAHHS AAHQN AAMNL AANHP AANLZ AAONW AASGY AAXRX AAYCA AAZKR ABCQN ABCUV ABEML ABIJN ABPVW ACAHQ ACBWZ ACCFJ ACCZN ACGFO ACGFS ACIWK ACMXC ACPOU ACPRK ACRPL ACSCC ACXBN ACXQS ACYXJ ADBBV ADEOM ADIZJ ADKYN ADMGS ADNMO ADOZA ADXAS ADZMN AEEZP AEGXH AEIGN AEIMD AENEX AEQDE AEUQT AEUYR AFBPY AFFPM AFGKR AFPWT AFRAH AFWVQ AFZJQ AHBTC AHMBA AIAGR AITYG AIURR AIWBW AJBDE AJXKR ALAGY ALMA_UNASSIGNED_HOLDINGS ALUQN ALVPJ AMBMR AMYDB ASPBG ATUGU AUFTA AVWKF AZBYB AZFZN AZVAB BAFTC BDRZF BFHJK BHBCM BLYAC BMNLL BMXJE BNHUX BROTX BRXPI BY8 CS3 D-E D-F DCZOG DPXWK DR1 DR2 DRFUL DRSTM DU5 EBD EBS EJD EMOBN F00 F01 F04 F5P FEDTE G-S G.N GNP GODZA H.T H.X HF~ HGLYW HHY HHZ HVGLF HZ~ IX1 J0M JPC KQQ LATKE LAW LC2 LC3 LEEKS LH4 LITHE LOXES LP6 LP7 LUTES LW6 LYRES MEWTI MK4 MRFUL MRSTM MSFUL MSSTM MXFUL MXSTM N04 N05 N9A NDZJH NF~ O66 O9- OIG P2P P2W P2X P4D PALCI PQQKQ Q.N Q11 QB0 QRW R.K RBB RIWAO RJQFR ROL RWI RX1 RYL SAMSI SUPJJ SV3 UB1 V2E V8K W8V W99 WBFHL WBKPD WIB WIH WIK WJL WOHZO WQJ WRC WSB WXSBR WYISQ XG1 XV2 Y6R ZZTAW ~IA ~WT AAMMB AAYXX AEFGJ AEYWJ AGHNM AGQPQ AGXDD AGYGG AIDQK AIDYY AIQQE CITATION O8X CGR CUY CVF ECM EIF NPM 7QO 8FD FR3 P64 7X8 |
| ID | FETCH-LOGICAL-c3469-fba66e2fb302033fe4dd9d2178a5e35dba9d064ef8a40efb05146432ebbd4083 |
| IEDL.DBID | DRFUL |
| ISICitedReferencesCount | 14 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000253781800003&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 1075-2617 |
| IngestDate | Sun Nov 09 12:32:11 EST 2025 Mon Oct 06 18:07:37 EDT 2025 Mon Jul 21 05:51:29 EDT 2025 Tue Nov 18 21:51:30 EST 2025 Sat Nov 29 04:15:06 EST 2025 Wed Jan 22 16:59:01 EST 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 2 |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c3469-fba66e2fb302033fe4dd9d2178a5e35dba9d064ef8a40efb05146432ebbd4083 |
| Notes | This article is part of the Special Issue of the Journal of Peptide Science entitled “Peptides in Nanotechnology”. ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Article-1 ObjectType-Feature-2 |
| PMID | 18044820 |
| PQID | 21153921 |
| PQPubID | 23462 |
| PageCount | 7 |
| ParticipantIDs | proquest_miscellaneous_70274375 proquest_miscellaneous_21153921 pubmed_primary_18044820 crossref_citationtrail_10_1002_psc_969 crossref_primary_10_1002_psc_969 wiley_primary_10_1002_psc_969_PSC969 |
| PublicationCentury | 2000 |
| PublicationDate | February 2008 2008-02-00 2008-Feb 20080201 |
| PublicationDateYYYYMMDD | 2008-02-01 |
| PublicationDate_xml | – month: 02 year: 2008 text: February 2008 |
| PublicationDecade | 2000 |
| PublicationPlace | Chichester, UK |
| PublicationPlace_xml | – name: Chichester, UK – name: England |
| PublicationTitle | Journal of peptide science |
| PublicationTitleAlternate | J Pept Sci |
| PublicationYear | 2008 |
| Publisher | John Wiley & Sons, Ltd |
| Publisher_xml | – name: John Wiley & Sons, Ltd |
| References | 2004; 33 2007; 19 2004; 303 1990; 35 2000 2006; 10 1997; 53 2004; 69 2002; 6 2005; 127 1970; 34 2007; 7 2005; 21 2005 2006; 2 2003; 1 2003; 125 2007; 208 2007; 88 2006; 128 2007; 46 2006; 202 1989 Atherton E (e_1_2_1_22_2) 1989 Berova N (e_1_2_1_25_2) 2000 e_1_2_1_23_2 e_1_2_1_20_2 e_1_2_1_21_2 e_1_2_1_26_2 e_1_2_1_27_2 e_1_2_1_24_2 e_1_2_1_28_2 Ozin GA (e_1_2_1_2_2) 2005 e_1_2_1_6_2 e_1_2_1_7_2 e_1_2_1_4_2 e_1_2_1_5_2 e_1_2_1_11_2 e_1_2_1_12_2 e_1_2_1_10_2 Ariga K (e_1_2_1_3_2) e_1_2_1_15_2 e_1_2_1_16_2 e_1_2_1_13_2 e_1_2_1_14_2 e_1_2_1_19_2 e_1_2_1_8_2 e_1_2_1_17_2 e_1_2_1_9_2 e_1_2_1_18_2 |
| References_xml | – volume: 35 start-page: 161 year: 1990 end-page: 214 publication-title: Int. J. Pept. Protein Res. – volume: 128 start-page: 696 issue: 3 year: 2006 end-page: 697 article-title: “Click peptide” based on the “O‐acyl isopeptide method”: Control of A beta 1–42 production from a photo‐triggered A beta 1–42 analogue publication-title: J. Am. Chem. Soc. – volume: 7 start-page: 136 issue: 2 year: 2007 end-page: 143 article-title: Functional, hierarchically structured poly(diacetylene)s via supramolecular self‐assembly publication-title: Macromol. Biosci. – year: 2005 – volume: 127 start-page: 17025 issue: 48 year: 2005 end-page: 17029 article-title: Light‐activated hydrogel formation via the triggered folding and self‐assembly of a designed peptide publication-title: J. Am. Chem. Soc. – volume: 46 start-page: 2681 issue: 15 year: 2007 end-page: 2684 article-title: Disruption of amyloid‐derived peptide assemblies through the controlled induction of a beta‐sheet to alpha‐helix transformation: application of the switch concept publication-title: Angewandte Chemie‐Int. Ed. – year: 1989 – volume: 128 start-page: 7722 issue: 24 year: 2006 end-page: 7723 article-title: Switch‐peptides to trigger the peptide guided assembly of poly(ethylene oxide)‐peptide conjugates into tape structures publication-title: J. Am. Chem. Soc. – year: 2000 – volume: 202 start-page: 19 year: 2006 end-page: 52 article-title: Synthesis of bio‐inspired hybrid polymers using peptide synthesis and protein engineering publication-title: Adv. Polym. Sci. – volume: 34 start-page: 595 year: 1970 article-title: Color test for detection of free terminal amino groups in the solid‐phase synthesis of peptides publication-title: Anal. Biochem. – volume: 69 start-page: 701 issue: 3 year: 2004 end-page: 713 article-title: Synthesis and activities of new C10 beta‐turn peptidomimetics publication-title: J. Org. Chem. – volume: 125 start-page: 7530 year: 2003 end-page: 7531 article-title: Photolytic control of peptide self‐assembly publication-title: J. Am. Chem. Soc. – volume: 88 start-page: 239 issue: 2 year: 2007 end-page: 252 article-title: Switch‐peptides as folding precursors in self‐assembling peptides and amyloid fibrillogenesis publication-title: Biopolymers – volume: 19 start-page: 1191 year: 2007 end-page: 1195 article-title: A highly ordered material from magnetically aligned peptide amphiphile nanofiber assemblies publication-title: Adv. Mater. – volume: 2 start-page: 822 issue: 10 year: 2006 end-page: 835 article-title: Peptide‐based stimuli‐responsive biomaterials publication-title: Soft Matter – volume: 21 start-page: 524 year: 2005 end-page: 526 article-title: Tuning secondary structure and self‐assembly of amphiphilic peptides publication-title: Langmuir – volume: 2 start-page: 1015 year: 2006 end-page: 1024 article-title: Self‐assembly and applications of biomimetic and bioactive peptide‐amphiphiles publication-title: Soft Matter – volume: 2 start-page: 177 issue: 3 year: 2006 end-page: 181 article-title: Biomimetic self‐assembled nanofibers publication-title: Soft Matter – volume: 208 start-page: 124 issue: 2 year: 2007 end-page: 130 article-title: Functional polymer‐bioconjugates as molecular LEGO (R) bricks publication-title: Macromol. Chem. Phys. – volume: 33 start-page: 234 year: 2004 end-page: 245 article-title: Peptide based amphiphiles publication-title: Chem. Soc. Rev. – volume: 6 start-page: 865 year: 2002 end-page: 871 article-title: Design of nanostructures biological materials through self‐assembly of peptides and proteins publication-title: Curr. Opin. Chem. Biol. – volume: 303 start-page: 1352 issue: 5662 year: 2004 end-page: 1355 article-title: Selective differentiation of neural progenitor cells by high‐epitope density nanofibers publication-title: Science – volume: 1 start-page: 1827 year: 2003 end-page: 1829 article-title: Non‐covalent stabilization of a beta‐hairpin peptide into liposomes publication-title: Org. Biomol. Chem. – volume: 10 start-page: 559 issue: 6 year: 2006 end-page: 567 article-title: Peptide‐based fibrous biomaterials: some things old, new and borrowed publication-title: Curr. Opin. Chem. Biol. – volume: 53 start-page: 3179 issue: 9 year: 1997 end-page: 3194 article-title: The use of Nbb‐resin for the solid‐phase synthesis of peptide alkylesters and alkylamides. Synthesis of leuprolide publication-title: Tetrahedron – ident: e_1_2_1_12_2 doi: 10.1002/macp.200600559 – ident: e_1_2_1_9_2 doi: 10.1039/b607706d – ident: e_1_2_1_27_2 doi: 10.1016/0003-2697(70)90146-6 – volume-title: Nanochemistry a Chemical Approach to Nanomaterials year: 2005 ident: e_1_2_1_2_2 – volume-title: Circular Dichroism: Principles and Applications year: 2000 ident: e_1_2_1_25_2 – ident: e_1_2_1_21_2 doi: 10.1002/adma.200602295 – ident: e_1_2_1_18_2 doi: 10.1021/ja060759w – ident: e_1_2_1_28_2 doi: 10.1016/S0040-4020(97)00029-X – ident: e_1_2_1_17_2 doi: 10.1002/bip.20663 – ident: e_1_2_1_26_2 doi: 10.1039/b303749e – ident: e_1_2_1_10_2 doi: 10.1016/j.cbpa.2006.09.019 – ident: e_1_2_1_19_2 doi: 10.1021/la047578x – ident: e_1_2_1_11_2 doi: 10.1002/mabi.200600226 – ident: e_1_2_1_15_2 doi: 10.1021/ja054719o – ident: e_1_2_1_23_2 doi: 10.1111/j.1399-3011.1990.tb00939.x – ident: e_1_2_1_5_2 doi: 10.1016/S1367-5931(02)00391-5 – ident: e_1_2_1_24_2 doi: 10.1021/jo034167x – ident: e_1_2_1_6_2 doi: 10.1126/science.1093783 – ident: e_1_2_1_8_2 doi: 10.1039/b516805h – ident: e_1_2_1_14_2 doi: 10.1021/ja035360b – volume-title: Bottom‐up Nanofabrication: Supramolecules, Self‐Assemblies, and Organized Films ident: e_1_2_1_3_2 – ident: e_1_2_1_4_2 doi: 10.1039/b212638a – ident: e_1_2_1_20_2 doi: 10.1002/anie.200603681 – ident: e_1_2_1_7_2 doi: 10.1039/b608929a – ident: e_1_2_1_13_2 doi: 10.1007/12_081 – volume-title: Solid Phase Peptide Synthesis year: 1989 ident: e_1_2_1_22_2 – ident: e_1_2_1_16_2 doi: 10.1021/ja057100v |
| SSID | ssj0009956 |
| Score | 1.8542451 |
| Snippet | In this paper, the introduction of both a methionine residue and a nitrobenzyl derivative as a labile linker between the peptide part and the hydrophobic alkyl... |
| SourceID | proquest pubmed crossref wiley |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 127 |
| SubjectTerms | caged peptides Circular Dichroism Microscopy, Electron, Transmission Molecular Structure nano‐fibres peptide amphiphiles Peptides - chemical synthesis Peptides - chemistry self‐assembly switching assembly |
| Title | Controlled disassembly of peptide amphiphile fibres |
| URI | https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fpsc.969 https://www.ncbi.nlm.nih.gov/pubmed/18044820 https://www.proquest.com/docview/21153921 https://www.proquest.com/docview/70274375 |
| Volume | 14 |
| WOSCitedRecordID | wos000253781800003&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVWIB databaseName: Wiley Online Library Full Collection 2020 customDbUrl: eissn: 1099-1387 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0009956 issn: 1075-2617 databaseCode: DRFUL dateStart: 19960101 isFulltext: true titleUrlDefault: https://onlinelibrary.wiley.com providerName: Wiley-Blackwell |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1LSwMxEB60inrx_aiPugfxtna7yT5ylGrxoEV8QG9LHhMo1LZ0q-C_d7K7tYoIgrCwlwkJM8nm-zaTbwDOFEaBJpbjM9aKfS609UVqjJ8UdR0IoUdcF8Umkm437fXE_ZdSX6U-xOcPN7cyiu-1W-BS5c25aOg41xciFouwFNKs5TVYunroPN_OFXdFUbqV6I1L42ol5Y1Z17hZNf2-Ff3Al9_harHfdDb-MdJNWK9ApndZzootWMDhNqy2Z7XdtmHlrjpS3wHWLpPVB2g8088JS-OLGrx7I-uNXcaLQU9SxPv0DNCzNBDMd-Gpc_3UvvGrSgq-ZsR_fatkHGNoFXMHj8wiN0YYYiOpjJBFRklhCJugTSUP0Conik5QJUSlDCeQtge14WiIB-AR4oicwI61UnJmudIK49Riy_A40ILV4Xzm00xXKuOu2MUgK_WRw4y8kZE36uB9Go5LYY2fJqezoGTkH3eSIYc4es0zYq0RAbvW7xaJo9ssieqwX0Zz3kkaECUNgzqcFUH7rffs_rFNr8O_mR3BWplJ4hJdjqE2nbziCSzrt2k_nzRgMemljWqGfgCzCejd |
| linkProvider | Wiley-Blackwell |
| linkToHtml | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1LSwMxEB60ivXi-1Ff3YN4W7ttso8cpVoq1lK0Qm_LJplAobbFVcF_72R3aylSEISFvUxImEk237eZfANwKdH3FLEcl7F64HKhjCsird0wq-tACN3nKis2EXa70WAgekVWpb0Lk-tD_Pxwsysj-17bBW5_SNfmqqHTVF2LQKzCGqdJ5Jdg7fap9dKZS-6KrHYr8Rubx1UP8yuztnGtaLq4F_0CmIt4NdtwWtv_GeoObBUw07nJ58UurOB4D8rNWXW3Pdh4LA7V94E183T1EWpHD1NC0_gqR1_OxDhTm_Oi0Uko5kN6RugYGgmmB9Bv3fWbbbeopeAqRgzYNTIJAmwYyezRIzPItRaa-EiU-Mh8LROhCZ2giRLuoZFWFp3ASgOl1Jxg2iGUxpMxHoNDmMO3EjvGJAlnhkslMYgM1jUPPCVYBa5mTo1VoTNuy12M4lwhuRGTN2LyRgWcH8NpLq3x26Q6i0pM_rFnGckYJx9pTLzVJ2hXX24RWsLNQr8CR3k4551EHpHShleByyxqy3qPe89Nep38zawK5Xb_sRN37rsPp7CZ55XYtJczKL2_feA5rKvP92H6dlFM1G8kluvl |
| linkToPdf | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1LSwMxEB7USvXi-1Ff3YN4W7ttso8cpbUo1lJ8QG_LJplAobalq4L_3snutqWIIAgLe5mQMJNsvm8z-QbgUqLvKWI5LmP1wOVCGVdEWrthVteBELrPVVZsIux2o35f9IqsSnsXJteHmP9wsysj-17bBY4TbWoL1dBJqq5FIFahxH0R0KIstZ7ar52F5K7IarcSv7F5XPUwvzJrG9eKpst70Q-AuYxXsw2nvf2foe7AVgEznZt8XuzCCo72YKM5q-62B-XH4lB9H1gzT1cfonb0ICU0jW9y-OWMjTOxOS8anYRiPqBniI6hkWB6AC_t25fmnVvUUnAVIwbsGpkEATaMZPbokRnkWgtNfCRKfGS-lonQhE7QRAn30Egri05gpYFSak4w7RDWRuMRHoNDmMO3EjvGJAlnhkslMYgM1jUPPCVYBa5mTo1VoTNuy10M41whuRGTN2LyRgWcueEkl9b4aVKdRSUm_9izjGSE4480Jt7qE7Sr_24RWsLNQr8CR3k4F51EHpHShleByyxqv_Ue956b9Dr5m1kVyr1WO-7cdx9OYTNPK7FZL2ew9j79wHNYV5_vg3R6UczTb84P62A |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Controlled+disassembly+of+peptide+amphiphile+fibres&rft.jtitle=Journal+of+peptide+science&rft.au=L%C3%B6wik%2C+Dennis+W.+P.+M.&rft.au=Meijer%2C+Joris+T.&rft.au=Minten%2C+Inge+J.&rft.au=van+Kalkeren%2C+Henri&rft.date=2008-02-01&rft.pub=John+Wiley+%26+Sons%2C+Ltd&rft.issn=1075-2617&rft.eissn=1099-1387&rft.volume=14&rft.issue=2&rft.spage=127&rft.epage=133&rft_id=info:doi/10.1002%2Fpsc.969&rft.externalDBID=10.1002%252Fpsc.969&rft.externalDocID=PSC969 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1075-2617&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1075-2617&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1075-2617&client=summon |