Cross-sectional evaluation of the Finnish Diabetes Risk Score: a tool to identify undetected type 2 diabetes, abnormal glucose tolerance and metabolic syndrome

The aim of this study was to assess the performance of the Finnish Diabetes Risk Score as a screening tool for undetected type 2 diabetes (T2D), abnormal glucose tolerance (AGT) and metabolic syndrome in the general population. In a cross-sectional, population-based survey, a total of 4,622 subjects...

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Veröffentlicht in:Diabetes & vascular disease research Jg. 2; H. 2; S. 67
Hauptverfasser: Saaristo, Timo, Peltonen, Markku, Lindström, Jaana, Saarikoski, Liisa, Sundvall, Jouko, Eriksson, Johan Gunnar, Tuomilehto, Jaakko
Format: Journal Article
Sprache:Englisch
Veröffentlicht: England 01.05.2005
Schlagworte:
Aged
Cardiovascular Diseases - etiology
Cross-Sectional Studies
Diabetes Mellitus, Type 2 - complications
Diabetes Mellitus, Type 2 - diagnosis
Diabetes Mellitus, Type 2 - epidemiology
False Positive Reactions
Female
Finland
Glucose Intolerance - complications
Glucose Intolerance - diagnosis
Glucose Intolerance - epidemiology
Humans
Male
Mass Screening
Metabolic Syndrome - complications
Metabolic Syndrome - diagnosis
Metabolic Syndrome - epidemiology
Middle Aged
Predictive Value of Tests
Prevalence
Risk Factors
ROC Curve
Surveys and Questionnaires
ISSN:1479-1641
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Zusammenfassung:The aim of this study was to assess the performance of the Finnish Diabetes Risk Score as a screening tool for undetected type 2 diabetes (T2D), abnormal glucose tolerance (AGT) and metabolic syndrome in the general population. In a cross-sectional, population-based survey, a total of 4,622 subjects aged 45-74 years were invited to a health examination that included an oral glucose tolerance test. Full data with risk score estimate and glucose tolerance status were available for 2,966 subjects without a prior history of diabetes. The risk score was associated with the presence of previously undiagnosed T2D, AGT, metabolic syndrome and cardiovascular risk factors. The area under the receiver operating curve for the prevalence of undiagnosed diabetes was 0.72 in men and 0.73 in women. The sensitivity using a cutoff risk score of 11 to identify undiagnosed diabetes was 66% in men and 70% in women; the corresponding false-positive rates were 31% and 39%, respectively. The area under the receiver operating curve for detecting the metabolic syndrome was 0.72 in men and 0.75 in women. The Finnish Diabetes Risk Score can be used as a self-administered test to screen subjects at high risk for T2D. It can also be used in the general population and clinical practice to identify undetected T2D, AGT and the metabolic syndrome.
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:1479-1641
DOI:10.3132/dvdr.2005.011