Tissue-resident memory CD8+ T cells promote melanoma–immune equilibrium in skin

The immune system can suppress tumour development both by eliminating malignant cells and by preventing the outgrowth and spread of cancer cells that resist eradication 1 . Clinical and experimental data suggest that the latter mode of control—termed cancer–immune equilibrium 1 —can be maintained fo...

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Bibliographic Details
Published in:	Nature (London) Vol. 565; no. 7739; pp. 366 - 371
Main Authors:	Park, Simone L., Buzzai, Anthony, Rautela, Jai, Hor, Jyh Liang, Hochheiser, Katharina, Effern, Maike, McBain, Nathan, Wagner, Teagan, Edwards, Jarem, McConville, Robyn, Wilmott, James S., Scolyer, Richard A., Tüting, Thomas, Palendira, Umaimainthan, Gyorki, David, Mueller, Scott N., Huntington, Nicholas D., Bedoui, Sammy, Hölzel, Michael, Mackay, Laura K., Waithman, Jason, Gebhardt, Thomas
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 17.01.2019
Subjects:	13 13/51 631/250/580/1884 631/67/1813/1634 Aged Animals CD8-Positive T-Lymphocytes - immunology Disease Progression Epidermis - immunology Epidermis - pathology Female Homeostasis - immunology Humanities and Social Sciences Humans Immunologic Memory - immunology Letter Male Melanoma, Experimental - immunology Melanoma, Experimental - pathology Mice Mice, Inbred C57BL Middle Aged multidisciplinary Neoplasm Transplantation Science Science (multidisciplinary) Skin - immunology Skin - pathology Skin Neoplasms - immunology Skin Neoplasms - pathology
ISSN:	0028-0836, 1476-4687, 1476-4687
Online Access:	Get full text
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