Correlation between retinal sensitivity and retinal vascular perfusion after idiopathic epiretinal membrane peeling

To evaluate the correlations between anatomical and functional changes after idiopathic epiretinal membrane (iERM) surgery. In this prospective, observational, single-center study, consecutive patients who underwent iERM peeling were enrolled. Reported data were pre- and postoperative best-corrected...

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Veröffentlicht in:European journal of ophthalmology Jg. 34; H. 4; S. 1228
Hauptverfasser: Nicolai, Michele, Franceschi, Alessandro, De Turris, Serena, Rosati, Alessandro, Carpenè, Maria Jolanda, Danieli, Luca, Lassandro, Nicola Vito, Pelliccioni, Paolo, Lupidi, Marco, Mariotti, Cesare
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States 01.07.2024
Schlagworte:
Aged
Epiretinal Membrane - physiopathology
Epiretinal Membrane - surgery
Female
Humans
Male
Middle Aged
Prospective Studies
Regional Blood Flow - physiology
Retina - diagnostic imaging
Retina - physiopathology
Retinal Vessels - diagnostic imaging
Retinal Vessels - physiopathology
Tomography, Optical Coherence
Visual Acuity - physiology
Visual Field Tests
Visual Fields - physiology
Vitrectomy
pars plana vitrectomy
anatomy/biochemistry/physiology
Epiretinal membrane
techniques of retinal examination
retinal pathology / research
ISSN:1724-6016, 1724-6016
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Zusammenfassung:To evaluate the correlations between anatomical and functional changes after idiopathic epiretinal membrane (iERM) surgery. In this prospective, observational, single-center study, consecutive patients who underwent iERM peeling were enrolled. Reported data were pre- and postoperative best-corrected visual acuity (BCVA), retinal sensitivity (RS) and fixation stability values on microperimetry, structural macular features on SD-OCT and OCTA. RS of foveal and parafoveal area was analysed and two sub-groups were identified whether RS improved or remained unchanged/worsened after surgery; consequently, vascular perfusion density (VPD) of the same area was studied. Twenty-nine eyes of 29 patients were examined. The post-operative improvement in terms of BCVA, RS and fixation within the central 4 degrees was significant (p < 0.001, p < 0.001, p = 0.001), as well as the foveal thickness and macular volume change/reduction (p < 0.001). The pre-operative superficial VPD, choriocapillaris VPD and capillary free zone (CFZ) area were significantly reduced compared to the fellow healthy eye (p = 0.001, p = 0.02, p < 0.001). Choriocapillaris VPD showed a statistically significant increase after surgery (p < 0.02). Superficial, deep and choriocapillaris VPD of the improved RS group showed a significant increase both in foveal (p = 0.03, p = 0.03, p = 0.01) and parafoveal areas (p = 0.01, p = 0.03, p = 0.001). We reported a higher VPD in the retinal area that experienced a retinal sensitivity improvement 6 months after ERM surgery. This result objectifies the tight bond between visual function and retinal perfusion in ERM patients.
Bibliographie:ObjectType-Article-1
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ISSN:1724-6016
1724-6016
DOI:10.1177/11206721231212823