Quantifying the coating yield by modeling heat and mass transfer in a Wurster fluidized bed coater

[Display omitted] •Full-physics CFD-DEM simulation of a pharmaceutical coating process.•Models for multicomponent spray evaporation and spray drying.•Possible reduction of coating losses from 28.2% to 6.1%•Evaluation of process robustness for various parameters. During the coating process of medicin...

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Bibliographic Details

Published in:	Chemical engineering science Vol. 252; p. 117505
Main Authors:	Madlmeir, S., Forgber, T., Trogrlic, M., Jajcevic, D., Kape, A., Contreras, L., Carmody, A., Liu, P., Davies, C., Sarkar, A., Khinast, J.G.
Format:	Journal Article
Language:	English
Published:	Elsevier Ltd 28.04.2022
Subjects:	CFD-DEM Coating Coating yield Multicomponent evaporation Spray drying Wurster coater Spray drying CFD-DEM Coating yield Coating Multicomponent evaporation Wurster coater
ISSN:	0009-2509, 1873-4405
Online Access:	Get full text
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