Characterization of a novel PERK kinase inhibitor with antitumor and antiangiogenic activity

The unfolded protein response (UPR) is a signal transduction pathway that coordinates cellular adaptation to microenvironmental stresses that include hypoxia, nutrient deprivation, and change in redox status. These stress stimuli are common in many tumors and thus targeting components of the UPR sig...

Celý popis

Podrobná bibliografia

Vydané v:	Cancer research (Chicago, Ill.) Ročník 73; číslo 6; s. 1993
Hlavní autori:	Atkins, Charity, Liu, Qi, Minthorn, Elisabeth, Zhang, Shu-Yun, Figueroa, David J, Moss, Katherine, Stanley, Thomas B, Sanders, Brent, Goetz, Aaron, Gaul, Nathan, Choudhry, Anthony E, Alsaid, Hasan, Jucker, Beat M, Axten, Jeffrey M, Kumar, Rakesh
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 15.03.2013
Predmet:	Adenine - analogs & derivatives Adenine - pharmacology Angiogenesis Inhibitors - pharmacology Animals Antineoplastic Agents - pharmacology eIF-2 Kinase - antagonists & inhibitors Female Gene Expression Profiling Indoles - pharmacology Mice Protein Kinase Inhibitors - pharmacology
ISSN:	1538-7445, 1538-7445
On-line prístup:	Zistit podrobnosti o prístupe
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!