Tubular Apocrine Adenoma with Uncertain Malignant Findings: Report of a Case and Review of the Literature

Introduction: Tubular apocrine adenoma (TAA) is a rare sweat gland tumor, usually presenting as a well-defined, red to brown nodule on the scalp. Generally, TAA is considered as benign tumor; however, it may be difficult to differentiate TAA from metastatic or primary carcinoma. Case Presentation: A...

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Vydáno v:Case reports in dermatology Ročník 17; číslo 1; s. 240 - 245
Hlavní autoři: Tokuchi, Keiko, Yanagi, Teruki, Maeda, Takuya, Nakazato, Shinichi, Miyamoto, Kodai, Tomaru, Utano, Anan, Takashi, Ujiie, Hideyuki
Médium: Journal Article
Jazyk:angličtina
Vydáno: Switzerland S. Karger AG 10.04.2025
Témata:
Single Case
Appendage tumors
Sweat gland tumor
Malignant findings
Tubular apocrine adenoma
Apocrine carcinoma
ISSN:1662-6567, 1662-6567
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Shrnutí:Introduction: Tubular apocrine adenoma (TAA) is a rare sweat gland tumor, usually presenting as a well-defined, red to brown nodule on the scalp. Generally, TAA is considered as benign tumor; however, it may be difficult to differentiate TAA from metastatic or primary carcinoma. Case Presentation: A woman in her 90s presented with a pale red nodule on her right posterior auricle for 3 years. Histology showed several tubular structures contained two layers in the dermis. These showed decapitation secretion. At the periphery of the lesion, squamoid tumor cells formed nest-like patterns. Some squamoid tumor cells exhibited multinucleation. Based on the histopathological, immunohistochemical, and molecular biology findings, the tumor was diagnosed as TAA with undefined malignant changes. Conclusion: TAA is a rare sweat gland neoplasm. Although TAA is generally benign, it can exhibit aggressive features, making thorough pathological evaluation crucial to rule out malignancy.
Bibliografie:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
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ObjectType-Report-1
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ISSN:1662-6567
1662-6567
DOI:10.1159/000545712