Peripheral neuropathy in non-Hodgkin's lymphoma patients receiving vincristine with and without aprepitant/fosaprepitant

Peripheral neuropathy is a common treatment-related adverse effect associated with vincristine. Vincristine is a major CYP3A4 substrate and is often administered alongside the neurokinin-1 (NK-1) receptor antagonists, aprepitant or fosaprepitant, which are moderate CYP3A4 inhibitors. This inhibition...

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Vydané v:	Journal of oncology pharmacy practice Ročník 26; číslo 4; s. 809
Hlavní autori:	Edwards, Jessi K, Bossaer, John B, Lewis, Paul O, Sant, Ashley
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England 01.06.2020
Predmet:	Aprepitant neuropathy vincristine fosaprepitant drug interaction
ISSN:	1477-092X, 1477-092X
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