Real-Time Genomic Profiling of Pancreatic Ductal Adenocarcinoma: Potential Actionability and Correlation with Clinical Phenotype

Molecular profiling in cancer has identified potential actionable drug targets that have prompted attempts to discover clinically validated biomarkers to guide therapeutic decision-making and enrollment to clinical trials. We evaluated whether comprehensive genetic analysis of patients with pancreat...

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Vydáno v:	Clinical cancer research Ročník 23; číslo 20; s. 6094
Hlavní autoři:	Lowery, Maeve A, Jordan, Emmet J, Basturk, Olca, Ptashkin, Ryan N, Zehir, Ahmet, Berger, Michael F, Leach, Tanisha, Herbst, Brian, Askan, Gokce, Maynard, Hannah, Glassman, Danielle, Covington, Christina, Schultz, Nikolaus, Abou-Alfa, Ghassan K, Harding, James J, Klimstra, David S, Hechtman, Jaclyn F, Hyman, David M, Allen, Peter J, Jarnagin, William R, Balachandran, Vinod P, Varghese, Anna M, Schattner, Mark A, Yu, Kenneth H, Saltz, Leonard B, Solit, David B, Iacobuzio-Donahue, Christine A, Leach, Steven D, O'Reilly, Eileen M
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 15.10.2017
Témata:	Carcinoma, Pancreatic Ductal - diagnosis Carcinoma, Pancreatic Ductal - genetics DNA Damage Female Gene Frequency Genetic Association Studies Genetic Testing Genetic Variation Genome-Wide Association Study Genomics High-Throughput Nucleotide Sequencing Humans Male Neoplasm Staging Oncogenes Pancreatic Neoplasms - diagnosis Pancreatic Neoplasms - genetics Phenotype
ISSN:	1078-0432, 1557-3265, 1557-3265
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