Real-Time Genomic Profiling of Pancreatic Ductal Adenocarcinoma: Potential Actionability and Correlation with Clinical Phenotype

Molecular profiling in cancer has identified potential actionable drug targets that have prompted attempts to discover clinically validated biomarkers to guide therapeutic decision-making and enrollment to clinical trials. We evaluated whether comprehensive genetic analysis of patients with pancreat...

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Bibliographic Details
Published in:	Clinical cancer research Vol. 23; no. 20; p. 6094
Main Authors:	Lowery, Maeve A, Jordan, Emmet J, Basturk, Olca, Ptashkin, Ryan N, Zehir, Ahmet, Berger, Michael F, Leach, Tanisha, Herbst, Brian, Askan, Gokce, Maynard, Hannah, Glassman, Danielle, Covington, Christina, Schultz, Nikolaus, Abou-Alfa, Ghassan K, Harding, James J, Klimstra, David S, Hechtman, Jaclyn F, Hyman, David M, Allen, Peter J, Jarnagin, William R, Balachandran, Vinod P, Varghese, Anna M, Schattner, Mark A, Yu, Kenneth H, Saltz, Leonard B, Solit, David B, Iacobuzio-Donahue, Christine A, Leach, Steven D, O'Reilly, Eileen M
Format:	Journal Article
Language:	English
Published:	United States 15.10.2017
Subjects:	Carcinoma, Pancreatic Ductal - diagnosis Carcinoma, Pancreatic Ductal - genetics DNA Damage Female Gene Frequency Genetic Association Studies Genetic Testing Genetic Variation Genome-Wide Association Study Genomics High-Throughput Nucleotide Sequencing Humans Male Neoplasm Staging Oncogenes Pancreatic Neoplasms - diagnosis Pancreatic Neoplasms - genetics Phenotype
ISSN:	1078-0432, 1557-3265, 1557-3265
Online Access:	Get more information
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