Kids in America: Newborn Screening for Cystic Fibrosis

Within the last year, all 50 states in the United States have adopted newborn screening (NBS) protocols for cystic fibrosis (CF), the most common fatal autosomal recessive disease among Caucasian populations. In this overview, we discuss the rationale for implementing NBS for CF and discuss the diff...

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Veröffentlicht in:Laboratory medicine Jg. 42; H. 10; S. 595 - 601
Hauptverfasser: Bender, Laura M., Cotten, Steven W., Willis, Monte S.
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Chicago Oxford University Press 01.10.2011
Schlagworte:
Adoption
Algorithms
Cystic fibrosis
Deoxyribonucleic acid
DNA
Genes
Genetic counseling
Medical genetics
Medical research
Medical screening
Mortality
Mutation
Newborn babies
Newborn infants
Proteins
Rodents
Studies
ISSN:0007-5027, 1943-7730
Online-Zugang:Volltext
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Beschreibung
Zusammenfassung:Within the last year, all 50 states in the United States have adopted newborn screening (NBS) protocols for cystic fibrosis (CF), the most common fatal autosomal recessive disease among Caucasian populations. In this overview, we discuss the rationale for implementing NBS for CF and discuss the different testing algorithms states have adopted. Based on studies in the United States, Australia, and the United Kingdom, these measures will likely lead to less severe disease, prolonged life, and more cost-effective management of CF in the long run. Keywords: cystic fibrosis, newborn screen, trypsinogen, IRT
Bibliographie:SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 14
ISSN:0007-5027
1943-7730
DOI:10.1309/LM80L3XIRBJUBNTH