Energy landscape analysis for regulatory RNA finding using scalable distributed cyberinfrastructure

SUMMARY We investigate the folding energy landscape for a given RNA sequence through Boltzmann ensemble (BE) sampling of RNA secondary structures. The ensemble of sampled structures is used to derive distributions of energies and base‐pair distances between two configurations. We identify structural...

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Bibliographic Details
Published in:	Concurrency and computation Vol. 23; no. 17; pp. 2292 - 2304
Main Authors:	Kim, Joohyun, Huang, Wei, Maddineni, Sharath, Aboul-ela, Fareed, Jha, Shantenu
Format:	Journal Article
Language:	English
Published:	Chichester, UK John Wiley & Sons, Ltd 10.12.2011
Subjects:	concurrent programming and distributed computing ncRNA gene finding Pilot-Job abstraction RNA folding energy landscape Simple API for Grid Applications (SAGA)
ISSN:	1532-0626, 1532-0634, 1532-0634
Online Access:	Get full text
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