Energy landscape analysis for regulatory RNA finding using scalable distributed cyberinfrastructure

SUMMARY We investigate the folding energy landscape for a given RNA sequence through Boltzmann ensemble (BE) sampling of RNA secondary structures. The ensemble of sampled structures is used to derive distributions of energies and base‐pair distances between two configurations. We identify structural...

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Veröffentlicht in:	Concurrency and computation Jg. 23; H. 17; S. 2292 - 2304
Hauptverfasser:	Kim, Joohyun, Huang, Wei, Maddineni, Sharath, Aboul-ela, Fareed, Jha, Shantenu
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Chichester, UK John Wiley & Sons, Ltd 10.12.2011
Schlagworte:	concurrent programming and distributed computing ncRNA gene finding Pilot-Job abstraction RNA folding energy landscape Simple API for Grid Applications (SAGA)
ISSN:	1532-0626, 1532-0634, 1532-0634
Online-Zugang:	Volltext
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