Neuroinflammation: An astrocyte perspective

Astrocytes are abundant glial cells in the central nervous system (CNS) that play active roles in health and disease. Recent technologies have uncovered the functional heterogeneity of astrocytes and their extensive interactions with other cell types in the CNS. In this Review, we highlight the intr...

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Vydáno v:Science translational medicine Ročník 15; číslo 721; s. eadi7828
Hlavní autoři: Lee, Hong-Gyun, Lee, Joon-Hyuk, Flausino, Lucas E, Quintana, Francisco J
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States 08.11.2023
Témata:
Astrocytes - metabolism
Central Nervous System
Humans
Inflammation - metabolism
Neuroglia
Neuroinflammatory Diseases
ISSN:1946-6242, 1946-6242
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Shrnutí:Astrocytes are abundant glial cells in the central nervous system (CNS) that play active roles in health and disease. Recent technologies have uncovered the functional heterogeneity of astrocytes and their extensive interactions with other cell types in the CNS. In this Review, we highlight the intricate interactions between astrocytes, other CNS-resident cells, and CNS-infiltrating cells as well as their potential therapeutic value in the context of inflammation and neurodegeneration.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ObjectType-Review-3
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ISSN:1946-6242
1946-6242
DOI:10.1126/scitranslmed.adi7828