PGE2 in fibrosis and cancer: Insights into fibroblast activation

•Fibroblasts are the main cells of connective tissue and participate in wound repair upon activation.•Unchecked fibroblast activation leads to fibrosis and contributes to cancer development.•PGE2 restricts fibroblast activation in fibrosis, thereby acting in an anti-fibrotic manner.•While PGE2 is co...

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Bibliographic Details

Published in:	Prostaglandins & other lipid mediators Vol. 143; p. 106339
Main Authors:	Elwakeel, Eiman, Brüne, Bernhard, Weigert, Andreas
Format:	Journal Article
Language:	English
Published:	Elsevier Inc 01.08.2019
Subjects:	Cancer COX Fibrosis mPGES-1 PGE2 PGE2 mPGES-1 COX Fibrosis Cancer
ISSN:	1098-8823
Online Access:	Get full text
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