Nr4a1 is required for fasting-induced down-regulation of Pparγ2 in white adipose tissue

Expression of the nuclear receptor gene, Nur77 (Nr4a1), is induced in white adipose tissue (WAT) in response to β-adrenergic stimulation and fasting. Recently, Nur77 has been shown to play a gene regulatory role in the fasting response of several other major metabolic tissues. Here we investigated t...

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Vydané v:	Molecular endocrinology (Baltimore, Md.) Ročník 27; číslo 1; s. 135
Hlavní autori:	Duszka, Kalina, Bogner-Strauss, Juliane G, Hackl, Hubert, Rieder, Dietmar, Neuhold, Claudia, Prokesch, Andreas, Trajanoski, Zlatko, Krogsdam, Anne-M
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 2013
Predmet:	3T3-L1 Cells Adipose Tissue, White - metabolism Animals Base Sequence Cell Nucleus - metabolism Consensus Sequence Down-Regulation Epididymis - metabolism Food Deprivation - physiology Gene Expression Regulation Gene Regulatory Networks Genes, Reporter Homeostasis Luciferases, Renilla - biosynthesis Luciferases, Renilla - genetics Male Mice Mice, Inbred C57BL Mice, Knockout Nuclear Receptor Subfamily 4, Group A, Member 1 - genetics Nuclear Receptor Subfamily 4, Group A, Member 1 - metabolism PPAR gamma - genetics PPAR gamma - metabolism Promoter Regions, Genetic Protein Binding Protein Transport Response Elements
ISSN:	1944-9917, 1944-9917
On-line prístup:	Zistit podrobnosti o prístupe
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