Disrupted static and dynamic Large-scale brain functional network connectivity in the differentiation of myelin oligodendrocyte glycoprotein Antibody-Seropositive from seronegative optic neuritis

Purpose The ability to distinguish myelin oligodendrocyte glycoprotein antibody-seropositive optic neuritis (MOG-ON) from seronegative-ON is critical in clinical practice. We investigate potential neural mechanisms and differentiation biomarkers via large-scale functional network connectivity (FNC)...

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Bibliographic Details
Published in:	Neuroradiology Vol. 67; no. 8; pp. 2107 - 2119
Main Authors:	Wang, Wentao, Liu, Xilan, Sha, Yan, Wang, Ximing, Lu, Ping
Format:	Journal Article
Language:	English
Published:	Berlin/Heidelberg Springer Berlin Heidelberg 01.08.2025 Springer Nature B.V
Subjects:	Adult Antibodies Autoantibodies - blood Biomarkers Biomarkers - blood Brain Brain research Case-Control Studies Clinical medicine Cluster analysis Diagnosis, Differential Differential diagnosis Differentiation Disease Dwell time Eye movements Female Functional magnetic resonance imaging Glycoproteins Humans Imaging Independent component analysis Magnetic resonance imaging Magnetic Resonance Imaging - methods Male Medicine Medicine & Public Health Middle Aged Myelin Myelin-Oligodendrocyte Glycoprotein - immunology Neural networks Neuritis Neuroimaging Neurology Neuroradiology Neurosciences Neurosurgery Oligodendrocyte-myelin glycoprotein Optic nerve Optic neuritis Optic Neuritis - blood Optic Neuritis - diagnostic imaging Optic Neuritis - immunology Optic Neuritis - physiopathology Radiology Software Time series Visual impairment Myelin oligodendrocyte glycoprotein Functional network connectivity Optic neuritis Independent component analysis
ISSN:	0028-3940, 1432-1920, 1432-1920
Online Access:	Get full text
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