Regulatory Phenomena in the Glutathione Peroxidase Superfamily

The selenium-containing Glutathione peroxidases (GPxs)1-4 protect against oxidative challenge, inhibit inflammation and oxidant-induced regulated cell death. GPx1 and GPx4 dampen phosphorylation cascades predominantly prevention of inactivation of phosphatases by H O or lipid hydroperoxides. GPx2 re...

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Bibliographic Details

Published in:	Antioxidants & redox signaling Vol. 33; no. 7; p. 498
Main Authors:	Brigelius-Flohé, Regina, Flohé, Leopold
Format:	Journal Article
Language:	English
Published:	United States 01.09.2020
Subjects:	alternate substrate reaction glutathione peroxidases ferroptosis inflammation-induced carcinogenesis transcriptional regulation apoptosis silencing of lipoxygenases
ISSN:	1557-7716, 1557-7716
Online Access:	Get more information
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