Comment on “Population Pharmacokinetics of Total and Unbound Isavuconazole in Critically Ill Patients: Implications for Adaptive Dosing Strategies” and “High Variability in Isavuconazole Unbound Fraction in Clinical Practice: A Call to Reconsider Pharmacokinetic/Pharmacodynamic Targets and Breakpoints”

Currently, there is no evidence that unbound isavuconazole concentrations are a better predictor of treatment response than total concentrations. [...]clinical implementation of monitoring unbound isavuconazole concentrations in routine clinical practice is difficult to justify. While isavuconazole...

Full description

Saved in:

Bibliographic Details
Published in:	Clinical pharmacokinetics Vol. 63; no. 5; pp. 731 - 733
Main Authors:	Kong, Leping, Alffenaar, Jan-Willem C., Stocker, Sophie L.
Format:	Journal Article
Language:	English
Published:	Cham Springer International Publishing 01.05.2024 Springer Nature B.V
Subjects:	Antibiotics Biomarkers Biosensors Clinical medicine Conflicts of interest Drug dosages Internal Medicine Laboratories Letter to the Editor Medicine Medicine & Public Health Pharmaceutical industry Pharmacodynamics Pharmacokinetics Pharmacology/Toxicology Pharmacotherapy Proteins Real time
ISSN:	0312-5963, 1179-1926, 1179-1926
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!