Evaluation of demographic and neuro-ophthalmologic findings of patients with multiple sclerosis

Purpose The study aims to investigate the demographic and neuroophthalmologic features of patients with multiple sclerosis (MS). Methods This retrospective study investigated 270 eyes of 135 patients with MS. All subjects underwent a full ophthalmological examination. Results The study investigated...

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Veröffentlicht in:International ophthalmology Jg. 44; H. 1; S. 356
Hauptverfasser: Orman, Gözde, Sungur, Gülten
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Dordrecht Springer Netherlands 25.08.2024
Springer Nature B.V
Schlagworte:
Adolescent
Adult
Autoimmune diseases
Demographics
Demography
Eye diseases
Female
Follow-Up Studies
Genetics
Humans
Male
Medicine
Medicine & Public Health
Middle Aged
Multiple sclerosis
Multiple Sclerosis - complications
Multiple Sclerosis - diagnosis
Multiple Sclerosis - epidemiology
Neuritis
Ophthalmology
Optic neuritis
Optic Neuritis - diagnosis
Optic Neuritis - epidemiology
Optic Neuritis - etiology
Original Paper
Retrospective Studies
Turkey - epidemiology
Visual Acuity
Visual observation
Visual pathways
Visual perception
Visual system
Young Adult
Turkey
Multiple sclerosis
Demography
Neuro-ophthalmology
Optic neuritis
ISSN:1573-2630, 0165-5701, 1573-2630
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Zusammenfassung:Purpose The study aims to investigate the demographic and neuroophthalmologic features of patients with multiple sclerosis (MS). Methods This retrospective study investigated 270 eyes of 135 patients with MS. All subjects underwent a full ophthalmological examination. Results The study investigated 270 eyes of 135 patients with MS. The patients included 102 (74.8%) females and 34 (25.2%) males. The mean age at the time of diagnosis of MS was 29.9 ± 9.6 years. The mean follow-up period was 6.7 ± 10.9 months. Initial symptoms of MS at presentation included optic neuritis (ON) in 42 patients (15.6%), numbness of hands and feet in 20 patients (7.4%) and diplopia in 11 patients (4.1%). Additional diseases were observed in 29 patients (21.5%) and autoimmune diseases were observed in 11 patients (8.1%). Thirteen patients (9.62%) had relatives with MS; the relatives of five patients were first-degree relatives and the relatives of the remaining eight patients were second-degree relatives. Table 2 summarizes the additional systemic and ocular diseases and family history data. During MS, 72 patients (53.4%) were diagnosed with ON. ON was bilateral in 49 patients (68%) and unilateral in 23 patients (32%). Retrobulbar ON was observed in 77 eyes (81.6%) and papillitis was observed in 18 eyes (18.4%). Disorders of efferent visual pathway function were found in 43 patients (30.4%). Conclusion Visual impairments are significant in patients with MS. Although ON is the most prevalent symptom of MS, it is important to keep in mind that damage to the efferent visual system can be observed.
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ISSN:1573-2630
0165-5701
1573-2630
DOI:10.1007/s10792-024-03285-5