A widespread plant defense compound disarms bacterial type III injectisome assembly

Numerous gram-negative bacterial pathogens employ the type III secretion system (T3SS), a multiprotein injectisome, to deliver virulence proteins into host cells and cause diseases. We uncover erucamide as a previously unknown phytoalexin of both dicots and monocots that blocks the T3SS function of...

Full description

Saved in:

Bibliographic Details
Published in:	Science (American Association for the Advancement of Science) Vol. 387; no. 6737; p. eads0377
Main Authors:	Miao, Pei, Wang, Haijun, Wang, Wei, Wang, Zhengdong, Ke, Han, Cheng, Hangyuan, Ni, Jinjing, Liang, Jingnan, Yao, Yu-Feng, Wang, Jizong, Zhou, Jian-Min, Lei, Xiaoguang
Format:	Journal Article
Language:	English
Published:	United States 28.02.2025
Subjects:	Arabidopsis - genetics Arabidopsis - immunology Arabidopsis - metabolism Arabidopsis - microbiology Arabidopsis Proteins - genetics Arabidopsis Proteins - metabolism Bacterial Outer Membrane Proteins - antagonists & inhibitors Bacterial Outer Membrane Proteins - metabolism Bacterial Proteins - metabolism Disease Resistance Erucic Acids - metabolism Erucic Acids - pharmacology Phytoalexins - metabolism Phytoalexins - pharmacology Plant Diseases - immunology Plant Diseases - microbiology Pseudomonas syringae - drug effects Pseudomonas syringae - pathogenicity Sesquiterpenes - chemistry Sesquiterpenes - metabolism Sesquiterpenes - pharmacology Type III Secretion Systems - antagonists & inhibitors Type III Secretion Systems - genetics Type III Secretion Systems - metabolism Virulence
ISSN:	1095-9203, 1095-9203
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!