Type-IIA secreted phospholipase A2 is an endogenous antibiotic-like protein of the host

Type-IIA secreted phospholipase A(2) (sPLA(2)-IIA) has been proposed to play a role in the development of inflammatory diseases. It has been shown to release arachidonic acid, the precursor of proinflammatory eicosanoids, to hydrolyze phospholipids of pulmonary surfactant, and to bind to specific re...

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Vydané v:	Biochimie Ročník 92; číslo 6; s. 583 - 587
Hlavní autori:	Wu, Yongzheng, Raymond, Benoît, Goossens, Pierre L., Njamkepo, Elisabeth, Guiso, Nicole, Paya, Miguel, Touqui, Lhousseine
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	France Elsevier 01.06.2010
Predmet:	Animals Anthrax - immunology Anti-Bacterial Agents - pharmacology Antigens, Bacterial - immunology Arachidonic Acid - metabolism Bacillus anthracis - immunology Bacillus anthracis - pathogenicity Bacterial Toxins - antagonists & inhibitors Drug Resistance, Microbial - immunology Group II Phospholipases A2 - metabolism Group II Phospholipases A2 - pharmacology Host-Pathogen Interactions Humans Immunology Life Sciences Mice Vaccinology
ISSN:	0300-9084, 1638-6183, 1638-6183
On-line prístup:	Získať plný text
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