The egg and the nucleus: a battle for supremacy

Sir John Gurdon and Professor Shinya Yamanaka were the recipients of the 2012 Nobel Prize for Physiology or Medicine. This Spotlight article is a commentary on the early nuclear transplant work in Xenopus, which was very important for the Nobel award in 2012, and the influence of this work on the re...

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Vydané v:Development (Cambridge) Ročník 140; číslo 12; s. 2449
Hlavný autor: Gurdon, J B
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: England 15.06.2013
Predmet:
Animals
Cell Differentiation
Cell Nucleus - genetics
Cell Nucleus - metabolism
Cellular Reprogramming
Cloning, Organism - history
Cloning, Organism - methods
Embryo, Nonmammalian - cytology
Embryo, Nonmammalian - embryology
Embryo, Nonmammalian - metabolism
Embryonic Development
Endoderm - cytology
Endoderm - metabolism
Epigenesis, Genetic
History, 20th Century
History, 21st Century
Mice
Nobel Prize
Nuclear Transfer Techniques - history
Ovum - cytology
Ovum - metabolism
Physiology - history
Xenopus - embryology
Xenopus - genetics
ISSN:1477-9129, 1477-9129
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Popis
Shrnutí:Sir John Gurdon and Professor Shinya Yamanaka were the recipients of the 2012 Nobel Prize for Physiology or Medicine. This Spotlight article is a commentary on the early nuclear transplant work in Xenopus, which was very important for the Nobel award in 2012, and the influence of this work on the reprogramming field.
Bibliografia:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1477-9129
1477-9129
DOI:10.1242/dev.097170