Metastasis of Melanoma to the Adrenal Glands: A Case Report and Literature Review

Immune checkpoint inhibitors have significantly improved the prognosis of metastatic melanoma, but metastases to the adrenal glands remain highly resistant to these new treatments. Adrenal gland metastases from melanoma can present in an unusual manner, such as in this report, making it diagnostical...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) Vol. 14; no. 7; p. e26749
Main Authors: Haider, Asad A, Ruiz de Villa, Ariel, Frimer, Leora, Bazikian, Yvette
Format: Journal Article
Language:English
Published: Palo Alto Springer Nature B.V 11.07.2022
Cureus
Subjects:
Abdomen
Blood clots
Case reports
Dermatology
Hematology
Immunotherapy
Kinases
Magnetic resonance imaging
Medical diagnosis
Medical imaging
Melanoma
Metastasis
Oncology
Skin cancer
ISSN:2168-8184, 2168-8184
Online Access:Get full text
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Summary:Immune checkpoint inhibitors have significantly improved the prognosis of metastatic melanoma, but metastases to the adrenal glands remain highly resistant to these new treatments. Adrenal gland metastases from melanoma can present in an unusual manner, such as in this report, making it diagnostically and therapeutically challenging. In this case report, we present a patient with histologically confirmed metastatic melanoma to the adrenal glands, a large intracardiac mass suspicious for metastatic disease, and an inferior vena cava thrombus. We review the existing literature to explain the unique characteristics, clinical relevance, pathogenesis, diagnosis, and treatment of adrenal gland metastases from melanoma.
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ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.26749