Multiple Positive Sweat Chloride Tests in an Infant Asymptomatic for Cystic Fibrosis
[...]one study reported that the percentage of infants diagnosed with CF increased with increasing IRT values (CF diagnosed in 1.6% of infants with IRT values <100 ng/mL, and in 48% of infants with IRT values >150 ng/mL).14 However, circulating trypsinogen levels cannot be used as a screening...
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| Vydáno v: | Laboratory medicine Ročník 43; číslo 2; s. 1 - 5 |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Journal Article |
| Jazyk: | angličtina |
| Vydáno: |
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Oxford University Press
01.02.2012
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| ISSN: | 0007-5027, 1943-7730 |
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| Abstract | [...]one study reported that the percentage of infants diagnosed with CF increased with increasing IRT values (CF diagnosed in 1.6% of infants with IRT values <100 ng/mL, and in 48% of infants with IRT values >150 ng/mL).14 However, circulating trypsinogen levels cannot be used as a screening test for CF in all age groups. Positive cultures or acquisition of Pseudomonas aeruginosa infection should be treated with anti-pseudomonal antibiotics and increased airway clearance even in the absence of symptoms.25 For evaluation of pulmonary function, the CF foundation recommends a baseline chest x-ray be obtained within the first 3-6 months of life and once again within the first 2 years of life in the presence or absence of symptoms.25 Patient Follow-Up and Treatment In addition to salt supplementation, the patient was started on a regimen of CF multivitamins and pancreatic enzyme supplementation (one-half capsule with feedings). |
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| AbstractList | [...]one study reported that the percentage of infants diagnosed with CF increased with increasing IRT values (CF diagnosed in 1.6% of infants with IRT values <100 ng/mL, and in 48% of infants with IRT values >150 ng/mL).14 However, circulating trypsinogen levels cannot be used as a screening test for CF in all age groups. Positive cultures or acquisition of Pseudomonas aeruginosa infection should be treated with anti-pseudomonal antibiotics and increased airway clearance even in the absence of symptoms.25 For evaluation of pulmonary function, the CF foundation recommends a baseline chest x-ray be obtained within the first 3-6 months of life and once again within the first 2 years of life in the presence or absence of symptoms.25 Patient Follow-Up and Treatment In addition to salt supplementation, the patient was started on a regimen of CF multivitamins and pancreatic enzyme supplementation (one-half capsule with feedings). |
| Author | Cotten, Steven W. Willis, Monte S. Bender, Laura M. |
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| SubjectTerms | Antibiotics Cystic fibrosis Diabetes Fluorides Hypothyroidism Medical screening Mutation Newborn babies Pancreas |
| Title | Multiple Positive Sweat Chloride Tests in an Infant Asymptomatic for Cystic Fibrosis |
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