Development of a subject-specific finite element analysis workflow to assess local biomechanics during segmental bone defect healing

Longitudinal estimation of local strain distributions within the regenerative niche of segmental femoral fractures is important for understanding mechanobiology principles for bone healing to design more effective rehabilitation regimens and mitigate nonunion complications. Finite element (FE) model...

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Bibliographic Details
Published in:	Journal of the mechanical behavior of biomedical materials Vol. 169; p. 107065
Main Authors:	Muhib, Farhan, Williams, Kylie E., LaBelle, Steven A., Lin, Angela S.P., Guldberg, Robert E., Weiss, Jeffrey A.
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Ltd 01.09.2025
Subjects:	Animals Biomechanical Phenomena Bone defect healing Femoral Fractures - diagnostic imaging Femoral Fractures - physiopathology Femur - diagnostic imaging Finite Element Analysis Fracture Healing Image mapping Male Mechanical Phenomena Rats Rats, Wistar Rehabilitation Stress, Mechanical Subject-specific modeling Workflow X-Ray Microtomography Bone defect healing Finite element analysis Rehabilitation Subject-specific modeling Image mapping
ISSN:	1751-6161, 1878-0180, 1878-0180
Online Access:	Get full text
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