Imaging tumour heterogeneity of the consequences of a PKCα-substrate interaction in breast cancer patients

Breast cancer heterogeneity demands that prognostic models must be biologically driven and recent clinical evidence indicates that future prognostic signatures need evaluation in the context of early compared with late metastatic risk prediction. In pre-clinical studies, we and others have shown tha...

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Veröffentlicht in:	Biochemical Society transactions Jg. 42; H. 6; S. 1498
Hauptverfasser:	Weitsman, Gregory, Lawler, Katherine, Kelleher, Muireann T, Barrett, James E, Barber, Paul R, Shamil, Eamon, Festy, Frederic, Patel, Gargi, Fruhwirth, Gilbert O, Huang, Lufei, Tullis, Iain D C, Woodman, Natalie, Ofo, Enyinnaya, Ameer-Beg, Simon M, Irshad, Sheeba, Condeelis, John, Gillett, Cheryl E, Ellis, Paul A, Vojnovic, Borivoj, Coolen, Anthony C C, Ng, Tony
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England 01.12.2014
Schlagworte:	Actin Depolymerizing Factors - metabolism Breast Neoplasms - enzymology Breast Neoplasms - metabolism Breast Neoplasms - pathology Cytoskeletal Proteins - metabolism Female Fluorescence Resonance Energy Transfer Humans Neoplasm Metastasis Phosphorylation Protein Kinase C-alpha - metabolism Subcellular Fractions - metabolism Substrate Specificity Treatment Outcome
ISSN:	1470-8752, 1470-8752
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