Epigenetically programmed identity crisis to combat diffuse large B cell lymphoma

A substantial fraction of patients with diffuse large B cell lymphoma (DLBCL) does not respond to standard-of-care immunochemotherapy.B cell differentiation is intimately associated with defined changes of the epigenetic landscape.DLBCL relies on epigenetic regulators to preserve their proproliferat...

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Bibliographic Details

Published in:	Trends in immunology
Main Authors:	Niccolai, Rachele, Göbel, Camiel, Jacobs, Heinz
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 07.11.2025
Subjects:	B cell differentiation cell identity diffuse large B cell lymphoma epigenetics germinal center cell identity germinal center B cell differentiation diffuse large B cell lymphoma epigenetics
ISSN:	1471-4906, 1471-4981, 1471-4981
Online Access:	Get full text
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