Epidemiological surveys revealed the risk of TAMV spill-over from ticks to hosts

Tick-borne viral diseases have become an increasingly important public health concern. Tamdy virus (TAMV) is a tick-borne virus of the genus in the family . While some studies have suggested that TAMV is a pathogen associated with human febrile illness, its epidemiology and the risk of TAMV spill-ov...

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Vydáno v:Infectious diseases (London, England) Ročník 56; číslo 1; s. 59 - 65
Hlavní autoři: Moming, Abulimiti, Bai, Yuan, Chen, Shengyao, Wu, Qiaoli, Wang, Jun, Jin, Jiayin, Tang, Shuang, Sun, Surong, Zhang, Yujiang, Shen, Shu, Deng, Fei
Médium: Journal Article
Jazyk:angličtina
Vydáno: England 2024
Témata:
Animals
Dogs
Humans
Phylogeny
RNA
Seroepidemiologic Studies
Sheep
Tick-Borne Diseases - epidemiology
Ticks
Zoonoses - epidemiology
epidemiology
spill-over
ticks
animal sera
Tamdy virus
Orthonairovirus
ISSN:2374-4235, 2374-4243, 2374-4243
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Shrnutí:Tick-borne viral diseases have become an increasingly important public health concern. Tamdy virus (TAMV) is a tick-borne virus of the genus in the family . While some studies have suggested that TAMV is a pathogen associated with human febrile illness, its epidemiology and the risk of TAMV spill-over remain poorly understood. Ticks were collected in Xinjiang, China, and grouped into pools. RT-PCR assays were used to detect TAMV RNA in these pools. The seroprevalence of TAMV was investigated using Immunofluorescence assays, Western blotting, and Luciferase immunoprecipitation system (LIPS) assays. TAMV RNA was detected in 17 out of 363 tick pools, resulting in a minimum infection rate (MIR) of 4.7%. and were identified as major tick vectors of TAMV. Phylogenetic analysis demonstrated that TAMV strains from Xinjiang are closely related to strains from other countries. Seroprevalence studies showed that TAMV exposure has been occurring in Xinjiang since at least 2006. Antibody responses to TAMV were detected in 1.1% (26/2296) of animals, including domestic animals and wild rodents. The seropositivity rates were as follows: sheep (1.7%), dog (2.3%), (0.8%), (3.5%). The research findings reveal that TAMV can be transmitted by ticks to various animal species, posing a significant public health risk. The wide distribution of TAMV and its tick vectors emphasise the importance of early preparedness and control measures. This study highlights the necessity for maintaining vigilance in addressing emerging zoonotic diseases transmitted by ticks.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:2374-4235
2374-4243
2374-4243
DOI:10.1080/23744235.2023.2270677