Microbial and Chemical Stability of Unpreserved Atropine Sulfate 0.01% w/w Eye Drops—A Pilot Study on the Impact of Dispenser Type and Storage Temperature over 12 Weeks of Daily Use After Compounding

Progressive myopia in children is a highly prevalent condition in societies worldwide and is often treated with compounded low-dose atropine sulfate (AS) eye drops without preserving agents to avoid irritation/sensitisation. Surprisingly, there is a lack of data regarding the in-use stability of con...

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Bibliographic Details
Published in:	Life (Basel, Switzerland) Vol. 15; no. 11; p. 1646
Main Authors:	Klang, Victoria, Brenner, Stefan, Grabner, Johanna, Unzeitig, Philip, Nguyen Hoang, My Vanessa, Lummerstorfer, Maria, Pichler, Roman, Steiner, Katja, Harvey, Richard D.
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 22.10.2025
Subjects:	Atropine atropine sulfate Backup software Cellulose acetate Clinical medicine Cold storage Contamination Corrosion resistance Dispensers Drug stores Eye care products High performance liquid chromatography homatropine hydrobromide in-use stability Inoculation Irritation Microorganisms Myopia Ophthalmic drugs Patient compliance pharmaceutical compounding Pharmaceuticals Pharmacy preservative-free dispenser progressive myopia Simulation Stability Storage temperature Sulfates Temperature Vision disorders in children Austria United States Switzerland Europe Germany United States > US homatropine hydrobromide preservative-free dispenser atropine sulfate contamination stress test progressive myopia pharmaceutical compounding in-use stability
ISSN:	2075-1729, 2075-1729
Online Access:	Get full text
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