Compression stiffness evaluation of polycaprolactone‐amorphous calcium phosphate 3D‐designed scaffolds oriented by finite element analysis

Scaffolds are implants used to accelerate bone regeneration process, being a relevant element of research in bone tissue engineering field. In this context, the proposal of this research was to perform a mechanical behavior evaluation, by finite element analysis (FEA), of two different configuration...

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Vydané v:Journal of applied polymer science Ročník 138; číslo 42
Hlavní autori: Liu, James, Roque, Renan, Barbosa, Gustavo Franco, Malavolta, Alexandre Tácito
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: Hoboken, USA John Wiley & Sons, Inc 10.09.2021
Wiley Subscription Services, Inc
Predmet:
Amorphous materials
biomaterials
biomedical applications
Biomedical materials
Calcium phosphates
Composite materials
composites
Compression tests
Configurations
Cost analysis
Finite element analysis
Finite element method
manufacturing
Materials science
Mechanical properties
Medical research
Multidisciplinary research
Polycaprolactone
Polymers
Regeneration (physiology)
Scaffolds
Stiffness
Surgical implants
Tissue engineering
ISSN:0021-8995, 1097-4628
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Shrnutí:Scaffolds are implants used to accelerate bone regeneration process, being a relevant element of research in bone tissue engineering field. In this context, the proposal of this research was to perform a mechanical behavior evaluation, by finite element analysis (FEA), of two different configurations of 3D scaffolds fabricated in a type of composite material of PCL‐ACP (polycaprolactone and amorphous calcium phosphate). The numerical results were compared with the experimental data and also, used to determine the compression stiffness of each studied scaffold configuration. Thus, it was possible to conclude that FEA is a tool that helps understand complex problems while being able to reduce time and cost in analysis, resulting in more efficient and less invasive medical procedures and treatments. In addition, the novelty of this multidisciplinary research work contributes as an application in tissue engineering area by relating a PCL‐ACP biomaterial with one unprecedented geometry of scaffold faced to FEA mechanical evaluation. Therefore, demonstrating to be a relevant subject for science by not only providing procedures that increases people's life quality but also for being a new application. Mechanical behavior of PLC‐ACP 3D printed scaffolds, according to stress analyzes performed by Finite Element Analysis (FEA) method. It presents the displacements and von Mises stresses obtained from the solutions, being possible to observe the deformations and the most critical stress points on the scaffolds.
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CNPq
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content type line 14
ISSN:0021-8995
1097-4628
DOI:10.1002/app.51245