Variability in SHBG assays and the effect thereof on calculated estimates of free testosterone

BackgroundSerum free testosterone is commonly used as a parameter to evaluate testosterone exposure and is mostly calculated using mathematical approximations. As the principal testosterone-binding protein, SHBG concentration is always included in such calculations. However, variability in SHBG meas...

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Bibliographic Details
Published in:	Annals of clinical biochemistry Vol. 62; no. 6; p. 493
Main Authors:	Walravens, Joeri, Adaway, Joanne, Reyns, Tim, Narinx, Nick, Nyamaah, Jennifer Afrakoma, Antonio, Leen, Kaufman, Jean-Marc, Keevil, Brian, Fiers, Tom, Lapauw, Bruno
Format:	Journal Article
Language:	English
Published:	England 01.11.2025
Subjects:	Adult Aged Chromatography, Liquid Female Humans Hyperandrogenism - blood Hyperandrogenism - diagnosis Hypogonadism - blood Hypogonadism - diagnosis Immunoassay - methods Male Middle Aged Sex Hormone-Binding Globulin - analysis Sex Hormone-Binding Globulin - metabolism Tandem Mass Spectrometry Testosterone - blood SHBG free testosterone immunoassay
ISSN:	1758-1001, 1758-1001
Online Access:	Get more information
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