Lessons Learned in Research and Development With Porcine Livers and the Clinical Translation—Beating the Organ Clock With Normothermic Machine Perfusion

ABSTRACT Short‐term (less than 24 h) normothermic liver perfusion devices are currently used in clinical practice. They improve logistics, simplify recipient matching, and aid in transplant decisions. At the same time, researchers globally are actively working on technologies to extend organ preserv...

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Bibliographic Details
Published in:	Clinical transplantation Vol. 39; no. 8; pp. e70264 - n/a
Main Authors:	Schuler, Martin Jörg, Becker, Dustin, Machacek, David, Kalt, Fabian, Fröhlich, Rafael, Lopez‐Lopez, Victor, Onder, Christopher, Oberholzer, Jose, Eshmuminov, Dilmurodjon
Format:	Journal Article
Language:	English
Published:	Denmark 01.08.2025
Subjects:	Animals Humans Liver Liver Transplantation - methods long‐term liver perfusion normothermic machine perfusion Organ Preservation - instrumentation Organ Preservation - methods Perfusion - instrumentation Perfusion - methods perfusion concept perfusion parameters perfusion protocol Swine Translational Research, Biomedical viability criteria viability criteria perfusion parameters perfusion protocol normothermic machine perfusion perfusion concept long‐term liver perfusion
ISSN:	0902-0063, 1399-0012, 1399-0012
Online Access:	Get full text
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